Temperature and pH affect enzyme activity. As with all other reactions, enzyme- catalyzed reactions _1___ in speed with an increase in temperature. However, as the temperature increases beyond a critical point, the protein structure begins to get disrupted resulting in 3 temperature and activity tends to decrease on either side of this temperature. Most human enzymes work best at around require nonprotein ___5_ such as zinc and manganese ions. Other enzymes may require organic inhibit enzyme activity. 7_ are so similar to the enzyme's substrate that they are able to enter the enzyme's active site and block the normal substrate from binding. This process is reversible and can be overcome by increasing the concentration of the enzyme's substrate. Another class of inhibitors does not affect an enzyme at its active site, they are called 2 _ and loss of enzyme function. Every enzyme has a(n) 4 _. Some enzymes 6. such as vitamin C and vitamin D. A variety of substances 8. Blank # 1 Blank # 2 Blank # 3 Blank # 4
Catalysis and Enzymatic Reactions
Catalysis is the kind of chemical reaction in which the rate (speed) of a reaction is enhanced by the catalyst which is not consumed during the process of reaction and afterward it is removed when the catalyst is not used to make up the impurity in the product. The enzymatic reaction is the reaction that is catalyzed via enzymes.
Lock And Key Model
The lock-and-key model is used to describe the catalytic enzyme activity, based on the interaction between enzyme and substrate. This model considers the lock as an enzyme and the key as a substrate to explain this model. The concept of how a unique distinct key only can have the access to open a particular lock resembles how the specific substrate can only fit into the particular active site of the enzyme. This is significant in understanding the intermolecular interaction between proteins and plays a vital role in drug interaction.
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