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A. Antibody enhancement of tumor growth Because attempts to immunize cancer patients by injecting specific antibodies that were developed in culture against their tumor cells often resulted in enhanced tumor growth, studies have been initiated to explore the mechanisms of antibody-induced tumor cel growth. The antitumor antibodies may bind to the antigens on the tumor cells, masking the antigens and blocking the ability of CTL cells to bind and kill the tumor cell. Antibody bound to tumor antigen may inhibit binding of Fc receptors on macrophages, dendritic cells, and NK cels.

A. Antibody enhancement of tumor growth Because attempts to immunize cancer patients by injecting specific antibodies that were developed in culture against their tumor cells often resulted in enhanced tumor growth, studies have been initiated to explore the mechanisms of antibody-induced tumor cel growth. The antitumor antibodies may bind to the antigens on the tumor cells, masking the antigens and blocking the ability of CTL cells to bind and kill the tumor cell. Antibody bound to tumor antigen may inhibit binding of Fc receptors on macrophages, dendritic cells, and NK cels.

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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A. Antibody enhancement of tumor growth Because attempts to immunize cancer patients by injecting specific antibodies that were developed in culture against their tumor cells often resulted in enhanced tumor growth, studies have been initiated to explore the mechanisms of antibody-induced tumor cell growth. The antitumor antibodies may bind to the antigens on the tumor cells, masking the antigens and blocking the ability of CTL cells to bind and kill the tumor cell. Antibody bound to tumor antigen may inhibit binding of Fc receptors on macrophages, dendritic cells, and NK cells.
Transcribed Image Text:A. Antibody enhancement of tumor growth Because attempts to immunize cancer patients by injecting specific antibodies that were developed in culture against their tumor cells often resulted in enhanced tumor growth, studies have been initiated to explore the mechanisms of antibody-induced tumor cell growth. The antitumor antibodies may bind to the antigens on the tumor cells, masking the antigens and blocking the ability of CTL cells to bind and kill the tumor cell. Antibody bound to tumor antigen may inhibit binding of Fc receptors on macrophages, dendritic cells, and NK cells.
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