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Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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lonic current through NMDA-gated channels is considered
A. Calcium dependent
B. Independent
C. AMPA dependent
D. Voltage dependent
Transcribed Image Text:lonic current through NMDA-gated channels is considered A. Calcium dependent B. Independent C. AMPA dependent D. Voltage dependent
Expert Solution
Step 1 Introduction on NMDA channels:

NMDA(  N methyl D aspartate receptor) is an ionotropic glutamate receptor fund in nerve cells. NMDA receptor is activated only when glutamate and glycine binds to it and the receptors when activated allows only positively charged ions to pass through it. There are important for their function in learning and memory. They are made of tetrameric ion channels composed of a family of related subunits. Aging in human population and decline in cognitive function is relevant to the depletion in NMDA receptor expression. Activation of the receptors results in opening of ion channels that is non selective to cations.

 

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