a) Write out the null and alternative hypothesis for the p –value annotated in the boxplot as p = 0.009.   H0:       HA:   b) Using a 0.05 significance level, briefly state your conclusion about this chemokine in context of the study:   c) Below is a table III. of correlations among various biomarkers for those with an intra-amniotic infection (IAI). List the variable pair(s) that have a statistically significant inverse relationship using a 0.002 significance level.

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The boxplots below compare various chemokines in amniotic fluid (GRO-α, interleukin-8, and L-selectin) in patients with (IAI) and without intra-amniotic infection (non-IAI).

Amniocentesis was performed on 45 pregnant women with preterm contractions, labor, or rupture of membranes. Fourteen patients had intra-amniotic infection, and 31 did not.  

a) Write out the null and alternative hypothesis for the p –value annotated in the boxplot as p = 0.009.

 

H0:

 

 

 

HA:

 

b) Using a 0.05 significance level, briefly state your conclusion about this chemokine in context of the study:

 

c) Below is a table III. of correlations among various biomarkers for those with an intra-amniotic infection (IAI).

List the variable pair(s) that have a statistically significant inverse relationship using a 0.002 significance level.

 

* p=0.009
* p<0.0001
* p<0.0001
of
10
1
AF L-selectin log10 (ng/mg Creatinine)
AF IL-8 log10 (ng/mg Creatinine)
L-selectin: IAI
Но
L-selectin: Non-IAI
IL-8: IAI
IL-8: Non-IAI
우
Gro-a.: IAI
HO
Gro-a.: Non-IAI
ood-
AF GRO-alpha log10 (ng/mg Creatinine)
Transcribed Image Text:* p=0.009 * p<0.0001 * p<0.0001 of 10 1 AF L-selectin log10 (ng/mg Creatinine) AF IL-8 log10 (ng/mg Creatinine) L-selectin: IAI Но L-selectin: Non-IAI IL-8: IAI IL-8: Non-IAI 우 Gro-a.: IAI HO Gro-a.: Non-IAI ood- AF GRO-alpha log10 (ng/mg Creatinine)
Table III. Correlations among amniotic fluid st-sclectin,
IL8, GRO-a, leukocytes, and glucose
Statistical
Variables
Correlation (1)
significance
sl-Selectin vs leukocytes
Sl-Selectin vs glucose
IL-8 vs leukocytes
IL8 vs glucose
GRO-a vs leukocytes
GRO-a vs glucose
p= 0.0237
p= 0.0022
p= 0.0002
p= 0.0041
p= 0.0015
p= 0.0017
0.349
-0.485
0.583
-0.454
0.495
-0.504
Transcribed Image Text:Table III. Correlations among amniotic fluid st-sclectin, IL8, GRO-a, leukocytes, and glucose Statistical Variables Correlation (1) significance sl-Selectin vs leukocytes Sl-Selectin vs glucose IL-8 vs leukocytes IL8 vs glucose GRO-a vs leukocytes GRO-a vs glucose p= 0.0237 p= 0.0022 p= 0.0002 p= 0.0041 p= 0.0015 p= 0.0017 0.349 -0.485 0.583 -0.454 0.495 -0.504
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