A study was conducted among patients with retinitis pigmentosa, an ocular condition where pigment appears over the retina, resulting in substantial loss of vision in many cases. The study was based on 94 patients who were seen annually at a baseline visit and three annual follow-up visits. In this study, 90 patients provided visual-field measurements at each of the four examinations and are the subject of the following data analyses. Visual field was transformed to the natural logarithm (ln) scale to better approximate normality and yielded the data given in the table below: Assuming that a change in visual field over 3 years is normally distributed when using the ln scale, what is the proportion of patients who showed a decline in visual field over 3 years? What percentage of patients would be expected to show a decline of at least 20% in visual field over 3 years? (Note: In the ln scale this is equivalent to a decline of at least ln (1/0.8) = 0.223). What percentage of patients would be expected to show a decline of at least 50% in visual field over 3 years?

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A study was conducted among patients with retinitis pigmentosa, an ocular condition where pigment appears over the retina, resulting in substantial loss of vision in many cases. The study was based on 94 patients who were seen annually at a baseline visit and three annual follow-up visits. In this study, 90 patients provided visual-field measurements at each of the four examinations and are the subject of the following data analyses. Visual field was transformed to the natural logarithm (ln) scale to better approximate normality and yielded the data given in the table below:

  1. Assuming that a change in visual field over 3 years is normally distributed when using the ln scale, what is the proportion of patients who showed a decline in visual field over 3 years?
  2. What percentage of patients would be expected to show a decline of at least 20% in visual field over 3 years? (Note: In the ln scale this is equivalent to a decline of at least ln (1/0.8) = 0.223).
  3. What percentage of patients would be expected to show a decline of at least 50% in visual field over 3 years?
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References
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English (United States)
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V
i.
Mailings
ii.
iii.
Review View
E
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V
V
Year of examination
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Year 3
Year 0
Year 3
* In (area of visual field) in degrees squared.
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Mean*
8.15
8.01
0.14
3
A study was conducted among patients with retinitis pigmentosa, an ocular condition where
pigment appears over the retina, resulting in substantial loss of vision in many cases. The study
was based on 94 patients who were seen annually at a baseline visit and three annual follow-up
visits. In this study, 90 patients provided visual-field measurements at each of the four
examinations and are the subject of the following data analyses. Visual field was transformed to
the natural logarithm (ln) scale to better approximate normality and yielded the data given in the
table below:
Tell me
AaBbCcDdEe
Normal
AaBbCcDdEe Aa BbCcDc AaBbCcDdE€ AaBb
No Spacing
Heading 1
Standard deviation
1.23
1.33
0.66
Heading 2
N
90
90
90
Assuming that a change in visual field over 3 years is normally distributed when
using the In scale, what is the proportion of patients who showed a decline in visual
field over 3 years?
What percentage of patients would be expected to show a decline of at least 20% in
visual field over 3 years? (Note: In the In scale this is equivalent to a decline of at
least In (1/0.8) = 0.223).
What percentage of patients would be expected to show a decline of at least 50% in
visual field over 3 years?
Focus
Title
Comments
AaBbCcDd Ee
Subtitle
Styles
Pane
I
Editing
Dictate
Share ✔
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+ 150%
Transcribed Image Text:AutoSave Home Insert Draw Design Layout Paste Page 2 of 2 Times New... V 12 v B I U 451 words A A ab x₂x² A v References Aa ✓ English (United States) + V i. Mailings ii. iii. Review View E - V V Year of examination Year 0 (baseline) Year 3 Year 0 Year 3 * In (area of visual field) in degrees squared. Developer → 2↓ Mean* 8.15 8.01 0.14 3 A study was conducted among patients with retinitis pigmentosa, an ocular condition where pigment appears over the retina, resulting in substantial loss of vision in many cases. The study was based on 94 patients who were seen annually at a baseline visit and three annual follow-up visits. In this study, 90 patients provided visual-field measurements at each of the four examinations and are the subject of the following data analyses. Visual field was transformed to the natural logarithm (ln) scale to better approximate normality and yielded the data given in the table below: Tell me AaBbCcDdEe Normal AaBbCcDdEe Aa BbCcDc AaBbCcDdE€ AaBb No Spacing Heading 1 Standard deviation 1.23 1.33 0.66 Heading 2 N 90 90 90 Assuming that a change in visual field over 3 years is normally distributed when using the In scale, what is the proportion of patients who showed a decline in visual field over 3 years? What percentage of patients would be expected to show a decline of at least 20% in visual field over 3 years? (Note: In the In scale this is equivalent to a decline of at least In (1/0.8) = 0.223). What percentage of patients would be expected to show a decline of at least 50% in visual field over 3 years? Focus Title Comments AaBbCcDd Ee Subtitle Styles Pane I Editing Dictate Share ✔ Editor + 150%
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