A study of patients with stage 1 breast cancer isrun to assess time to progression to stage II over an observation period of15 years. Of interest is whether there is a difference in time to progressionbetween patients on two different chemotherapy regimens. Times toprogression are measured in years from the time at which thechemotherapy regimen was initiated.(using Excel and show the table)A) Estimate the survival functions (times to progression) for eachchemotherapy regimen using the Kaplan-Meier approach.B) Sketch the two survival functions above.C) Test whether there is a significant difference in time to progressionbetween treatment regimens using the log-rank test and a 5% level ofsignificance.D) Compute and interpret the hazard ratio for progression to stage II withthe regimen I as compared to regimen 2.Years to progression by chemotherapy regimenRegimen 11Progression No progression121413111510826734612Regimen 2Progression No progression9114147139141369

Given the data of a study of patients with stage I breast cancer is run to assess time to…

Answered: A study of patients with stage 1 breast…

MATLAB: An Introduction with Applications

6th Edition

ISBN:9781119256830

Author:Amos Gilat

Publisher:Amos Gilat

Chapter1: Starting With Matlab

Section: Chapter Questions

Problem 1P

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The null hypothesis: H. :|| The alternative hypothesis: H :0 1 The type of test statistic: (Choose one) v The value of the test statistic: (Round to at least three decimal places.) The p-value: (Round to at least three decimal places.) Can we reject the researchers' claim that the mean recovery time when treated with multivitamin is less than or equal to the mean recovery time when treated with vitamin C only? Yes No
People gain weight when they take in more energy from food than they expend. Researchers wanted to investigate the link between obesity and energy spent on daily activity. Choose 20 healthy volunteers who don't exercise. Deliberately choose 10 who are lean and 10 who are mildly obese but still healthy. Attach sensors that monitor the subjects' every move for 10 days. The table below presents data on the time (in minutes per day) that the subjects spent standing or walking, sitting, and lying down. Is there a significant difference between the mean times the two groups spend lying down? Let ?1 be the mean time spent lying down by the lean group, and ?2 be the mean time for the obese group. Time (minutes per day) spent in three different postures by leanand obese subjects Group Subject Stand/Walk Sit Lie Lean 1 509.100 366.300 554.500 Lean 2 603.925 374.512 452.650 Lean 3 322.212 580.138 533.362 Lean 4 581.644 362.144 489.269 Lean 5…
A study is run to estimate the incidence of atrial fibrillation (AF) in men and women over the age of 60. Development of atrial fibrillation was monitored over a 10-year follow-up period. The data are summarized below. Using this data, compute the cumulative incidence of AF in men and in women respectively. Developed AF Did not Develop AF Men 120 6453 Women 86 7074
Table 4 above is displaying odds ratios for each predictor estimated by a multivariablelogistic regression model with all 6 predictors included at the same time. Based onthis model, what is the minimum number of in-hospital deaths they should have intheir dataset? A) 30 B) 50 C) 60 D) 70
use calculator method
A new screening test for Lyme disease is developed for use in the general population. The sensitivity and specificity of the new test are 60% and 70%, respectively. Five hundred people are screened at a clinic during the first year the new test is implemented. Assume the true prevalence of Lyme disease among clinic attendees is 10%. Calculate the predictive value of a positive test.
A researcher has developed a new drug designed to reduce blood pressure. In an experiment, 22 subjects were assigned randomly to the treatment group and received the new experimental drug. The other 24 subjects were assigned to the control group and received a standard, well-known treatment. After a suitable period, the reduction in blood pressure for each subject was recorded. A summary of these data is: nn x¯x¯ ss Treatment group (new drug) 22 23.48 8.01 Control group (old drug) 24 18.52 7.15 Without using software, how would you estimate the number of degrees of freedom for this problem? Select one: use the larger value, 23, chosen from the two options 21 and 23 use the smaller value, 22, chosen from the two options 22 and 24 use the larger value, 24, chosen from the two options 22 and 24 use the smaller value, 21, chosen from the two options 21 and 23
The contingency table shows the results of a random sample of patients from musculoskeletal injuries treated with acetaminophen or ibuprofen. At a=0.10, can you conclude that the treatment is related to the result? Result acetaminophen Ibuprofen Significant improvement 58 81 Slight improvement 42 19
The mango is considered the "king of fruits" in many parts of the world. Mangoes are generally harvested at the mature green stage and ripen up during the marketing process of transport, storage, and so on. During this process, about 30% of the fruit is wasted. Because of this, the impact of harvest stage and storage conditions on the postharvest quality are of interest. In this experiment, the fruit was harvested at 80, 95, or 110 days after the fruit setting (the transition from flower to fruit) and then stored at temperatures of 20∘C, 30∘C, or 40∘C. For each harvest time and storage temperature, a random sample of mangoes was selected, and the time to ripening was measured. What are the factors, the treatments, and the response variables? Take each item from the answer bank and place into the appropriate category.
In a population-based cohort study, an entire community was interviewed regarding smoking habits and then followed for one year. Upon ascertainment of all lung cancer deaths, the investigator obtained the following data: Number of Individuals Lung Cancer Deaths Smokers 24,500 15 Nonsmokers 10,500 2 Calculate the risk difference per 100,000 per year. Round to the tenth decima
A study is run to estimate the incidence of atrial fibrillation (AF) in men and women over the age of 60. Development of atrial fibrillation was monitored over a 10-year follow-up period. The data are summarized below. Using this data, compute the cumulative incidence of AF in men and in women respectively. Developed AF Did not Develop AF Men 133 6153 Women 79 7167
Ankylosing spondylitis is an inflammatory disease which affects the spine and sacroiliac joint and can lead to the fusing of vertebrae in the spine. Exercise is important in helping manage pain, therefore a pharmaceutical company wanted to test if their new biologic would increase the time a patient could exercise before experiencing discomfort. The following table gives the time (in minutes) seven patients were able to exercise before reporting pain, both at baseline and then again after six months of taking the biologic.Exercise Time (in minutes)Subject 1 Baseline 30 Post-treatment 40Subject 245 40Subject 350 60Subject 435 37Subject 555 60Subject 620 25Subject 775 75Assume the population(s) of all exercise times is (are) normally distributed. Use JMP to test whether the evidence suggests that the time a person with ankylosing spondylitis can exercise before experiencing discomfort increases after taking this new biologic. Validate the test statistic from JMP by computing it manually.…

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