A study of patients with stage 1 breast cancer isrun to assess time to progression to stage II over an observation period of15 years. Of interest is whether there is a difference in time to progressionbetween patients on two different chemotherapy regimens. Times toprogression are measured in years from the time at which thechemotherapy regimen was initiated.(using Excel and show the table)A) Estimate the survival functions (times to progression) for eachchemotherapy regimen using the Kaplan-Meier approach.B) Sketch the two survival functions above.C) Test whether there is a significant difference in time to progressionbetween treatment regimens using the log-rank test and a 5% level ofsignificance.D) Compute and interpret the hazard ratio for progression to stage II withthe regimen I as compared to regimen 2.Years to progression by chemotherapy regimenRegimen 11Progression No progression121413111510826734612Regimen 2Progression No progression9114147139141369

Given the data of a study of patients with stage I breast cancer is run to assess time to…

Answered: A study of patients with stage 1 breast…

MATLAB: An Introduction with Applications

6th Edition

ISBN:9781119256830

Author:Amos Gilat

Publisher:Amos Gilat

Chapter1: Starting With Matlab

Section: Chapter Questions

Problem 1P

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Cardiovascular Disease Suppose the incidence rate of myocardial infarction (MI) was 5 per 1000 among 45- to 54-year-old men in 2000. To look at changes in incidence over time, 5000 men in this age group were followed for 1 year starting in 2010. Fifteen new cases of MI were found. 7.14 Of the 15 new MI cases in the preceding study, 5 died within 24 hours. Test whether the 24-hour case- fatality rate changed from 2000 to 2010.
A new screening test for Lyme disease is developed for use in the general population. The sensitivity and specificity of the new test are 60% and 70%, respectively. Five hundred people are screened at a clinic during the first year the new test is implemented. Assume the true prevalence of Lyme disease among clinic attendees is 10%. Calculate the predictive value of a positive test.
A researcher has developed a new drug designed to reduce blood pressure. In an experiment, 22 subjects were assigned randomly to the treatment group and received the new experimental drug. The other 24 subjects were assigned to the control group and received a standard, well-known treatment. After a suitable period, the reduction in blood pressure for each subject was recorded. A summary of these data is: nn x¯x¯ ss Treatment group (new drug) 22 23.48 8.01 Control group (old drug) 24 18.52 7.15 Without using software, how would you estimate the number of degrees of freedom for this problem? Select one: use the larger value, 23, chosen from the two options 21 and 23 use the smaller value, 22, chosen from the two options 22 and 24 use the larger value, 24, chosen from the two options 22 and 24 use the smaller value, 21, chosen from the two options 21 and 23
The contingency table shows the results of a random sample of patients from musculoskeletal injuries treated with acetaminophen or ibuprofen. At a=0.10, can you conclude that the treatment is related to the result? Result acetaminophen Ibuprofen Significant improvement 58 81 Slight improvement 42 19
A study is run to estimate the incidence of atrial fibrillation (AF) in men and women over the age of 60. Development of atrial fibrillation was monitored over a 10-year follow-up period. The data are summarized below. Using this data, compute the cumulative incidence of AF in men and in women respectively. Developed AF Did not Develop AF Men 133 6153 Women 79 7167
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Ankylosing spondylitis is an inflammatory disease which affects the spine and sacroiliac joint and can lead to the fusing of vertebrae in the spine. Exercise is important in helping manage pain, therefore a pharmaceutical company wanted to test if their new biologic would increase the time a patient could exercise before experiencing discomfort. The following table gives the time (in minutes) seven patients were able to exercise before reporting pain, both at baseline and then again after six months of taking the biologic.Exercise Time (in minutes)Subject 1 Baseline 30 Post-treatment 40Subject 245 40Subject 350 60Subject 435 37Subject 555 60Subject 620 25Subject 775 75Assume the population(s) of all exercise times is (are) normally distributed. Use JMP to test whether the evidence suggests that the time a person with ankylosing spondylitis can exercise before experiencing discomfort increases after taking this new biologic. Validate the test statistic from JMP by computing it manually.…
A random selection of volunteers at a research institute have been exposed to a typical cold virus. After they started to have cold symptoms, 15 of them were given multivitamin tablets formulated to fight cold symptoms. The remaining 15 volunteers were given placebo tablets. For each individual, the length of time taken to recover from the cold is recorded. At the end of the experiment the following data are obtained. Days to recover from a cold Treated with multivitamin Treated with placebo 3.0, 5.6, 1.5, 6.8, 3.8, 7.5, 5.8, 4.6, 2.4, 5.0, 7.5, 5.0, 2.6, 1.7, 6.7 4.9, 6.1, 4.9, 4.2, 3.4, 5.5, 5.6, 3.4, 7.9, 6.8, 4.8, 4.2, 5.7, 2.2, 4.0 Send data to Excel Send data to calculator It is known that the population standard deviation of recovery time from a cold is 1.8 days when treated with multivitamin tablets, and the population standard deviation of recovery time from a cold is 1.5 days when treated with placebo tablets. It is also known that both populations are approximately normally…
Lecture(8.8): The amount of time people engage in physical activity mat be related to health outcome. Those who report that they spend more than 15 hours are put into one while those who spend less 10 were put into another group. (Those who fall in between 10 and 15 were left out of the study); The reaearcher then ask the participants to wear a monitor for one month. The average time in minutes is recorded and shown below . Is there any evidence that on average people who watch less than 10 hours watching televsion spend more time on physical activity.?. Test the hypotheses at (alpha=0.05) using the 5 step procedure <10 hours 75 63 118 35 82 >15 hours 62 6 78 43 22 33
The relationship between United States unemployment and inflation rates during the Covid-19 pandemic. Background The covid-19 pandemic has led to higher unemployment rates in the United States than normal because many people were laid off jobs in response to the pandemic (Al-Fadly, 2020). It is important to analyze how such as sharp increase in unemployment affected inflation in relation to how unemployment have traditionally affected inflation. The overall relationship between unemployment and inflation has traditionally been an inverse one. It is argued that when unemployment rates are higher, the number of individuals who are looking for jobs usually becomes higher than the number of job positions that are available (Putnam & Azzarello, 2015). In such a situation, employers tend to pay lower wages because there is abundance of workers which naturally leads to a lower wage inflation. This study will examine the relationship between unemployment rates and inflation rate during…
According to a JHU study published in the American Journal of Public Health, widows live longer than widowers. Consider the following survival data collected on 100 widows and 100 widowers following the death of spouse: Years Lived Widow Widower Less than 5 25 39 5 to 10 42 40 More Than 10 33 21 Can we conclude at 0.05 level of significance that the proportions of widows and widowers are equal with respect to the different time periods that a spouse survives after the death of his or her mate?

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