A drug treatment can sometimes be affected by the use of another drug taken concomitantly. This is why doctors andpharmacists routinely ask patients about all the drugs they use, even the ones available over the counter. One study examinedthe impact of nonsteroidal anti-inflammatory drugs (NSAIDs) on the efficacy of the antidepressant citalopram in clinicallydepressed individuals. Data from a large clinical trial were reviewed, and clinical remission from depressive symptoms wasassessed for individuals who had taken NSAIDs concomitantly and those who had not. The findings are given in the table.NSAID useNo NSAID useRemission182628No remission227509How strong is the evidence that concomitant NSAID use lowers the effectiveness of the antidepressant citalopram? Followthe four-step process. SOLVE: Determine the sample proportions, p₁ and P2, and the pooled sample proportion, p. Give your answers to fourdecimal places.P₁ =P₂p=0.4461Incorrect0.5511Incorrect0.5233IncorrectEnter numeric value

Given data: Remission No remission NSAID use 182 227 No NSAID use 628 509

Answered: A drug treatment can sometimes be…

MATLAB: An Introduction with Applications

6th Edition

ISBN:9781119256830

Author:Amos Gilat

Publisher:Amos Gilat

Chapter1: Starting With Matlab

Section: Chapter Questions

Problem 1P

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Hyperhidrosis is a stressful medical condition characterized by chronic excessive sweating. Botox was approved for treatment of hyperhidrosis in adults in 2004. A clinical trial examined the effectiveness of Botox for excessive armpit sweating in teenagers aged 12 to 17 years. Participants received either a Botox injection or a placebo injection (a simple saline solution) and were examined four weeks later to see if their sweating had been reduced. Here are the study's findings: Botox Placebo Total Reduced Confidence Interval: 72 52 124 Not Reduced 28 We are 95% confident that there is hyperhidrosis who experienced a reduction in sweating. 148 176 Total 100 200 - Construct a 95% confidence interval for p₁ - P2 where p₁ denotes the proportion of teenagers who experienced a reduction in sweating in the Botox group and p2 denotes the proportion of teenagers who experienced a reduction in sweating in the placebo group. Round your answers to three decimal places, and use four decimal places…
The Diabetes Control and Complications trial research group, randomly assigned volunteers with type 1 (insulin-dependent) diabetes mellitus, but without retinopathy, either to a conventional treatment or to a more intensive treatment aimed at maintaining normal blood glucose levels. The volunteers' health was monitored closely for approximately six years. By the end of the study, 91 patients out of 378 in the conventional treatment group had developed retinopathy, whereas 23 out of 348 in the intensive treatment group had developed retinopathy. Test whether the rates of retinopathy differed significantly between the two treatment groups, if they did, which rate was significantly lower. 1. Provide the null hypothesis 2. Provide the alternative hypotheses 3. calculate the appropriate test statistic. Show all work 4. Identify the p-value for that test statistic 5. Using the p-value method and an alpha level of 0.02 state what your conclusions are regarding the null hypothesis, and…
A deficiency of the trace element selenium in the diet can negatively impact growth, immunity, muscle and neuromuscular function, and fertility. The introduction of selenium supplements to dairy cows is justified when pastures have low selenium levels. Authors of a research paper supplied the following data on milk selenium concentration (mg/L) for a sample of cows given a selenium supplement (the treatment group) and a control sample given no supplement, both initially and after a 9-day period. Initial Measurement Treatment Control 11.4 9.1 9.6 8.7 10.1 9.7 8.5 10.8 10.2 10.9 10.6 10.6 11.9 10.1 9.9 12.3 10.7 8.8 10.2 10.4 10.3 10.9 11.4 10.4 9.3 11.6 10.6 10.9 10.9 8.3 After 9 Days Treatment Control 138.3 9.2 104 8.9 96.4 8.9 89 10.1 88 9.6 103.8 8.6 147.3 10.4 97.1 12.4 172.6 9.2 146.3 9.5 99 8.4 122.3 8.8 103 12.5 117.8 9.1 121.5 93 (a) Use the given data for the treatment group to determine if…
A researcher suspects that the actual prevalence of generalized anxiety among children and adolescents is higher than the previously reported prevalence of generalized anxiety disorder among children and adolescents. The previously reported prevalence of generalized anxiety disorder among children and adolescents is 3.9%, and the researcher conducts a study to test the accuracy of the previously reported prevalence of generalized anxiety disorder by recruiting 98 children and adolescents from various pediatricians’ offices and tests them for generalized anxiety disorder using the DSM-5. The researcher determines that the prevalence of generalized anxiety disorder among the participants of the study is 6.1%. The researcher’s hypothesis, for a level of significance of 5%, should resemble which of the following sets of hypothesis? A) H0: p > .039; H1: p = .039; alpha= .05 B) H0: p = .039; H1: p > .039; alpha= .05 C) H0: p > .039; H1: p = .039; alpha= .95 D) H0: p = .039; H1: p…
Read the journal excerpt below:Exposure to light at night suppresses the physiologic production of melatonin, a hormone that has antiproliferative effects on intestinal cancers. Although observational studies have associated night-shift work with an increased risk of breast cancer, the effect of night-shift work on the risk of other cancers is not known. We examined the relationship between working rotating night shifts and the risk of colorectal cancers among female participants in the Nurses’ Health Study. We documented 602 incident cases of colorectal cancer among 78 586 women who were followed up from 1988 through 1998. Compared with women who never worked rotating night shifts, women who worked 15 years or more on rotating night shifts were 1.35 times more likely to develop colorectal cancer (95% CI = 1.03 to 1.77), adjusting for confounders. These data suggest that working a rotating night shift at least three nights per month for 15 or more years may increase the risk of…
A researcher suspects that the actual prevalence of generalized anxiety among children and adolescents is higher than the previously reported prevalence of generalized anxiety disorder among children and adolescents. The previously reported prevalence of generalized anxiety disorder among children and adolescents is 3.9%, and the researcher conducts a study to test the accuracy of the previously reported prevalence of generalized anxiety disorder by recruiting 98 children and adolescents from various pediatricians’ offices and tests them for generalized anxiety disorder using the DSM-5. The researcher determines that the prevalence of generalized anxiety disorder among the participants of the study is 6.1%. Calculate the z value for the test statistic. A) z = 1.12 B) z = 1.09 C) z = 0.92 D) z = -57.53
You are concerned that nausea may be a side effect of Tamiflu, but you cannot just give Tamiflu to patients with the flu and say that nausea is a side effect if people become nauseous. This is because nausea is common for people who have the flu. From past studies you know that about 30% of people who get the flu experience nausea. You collected data on 1744 patients who were taking Tamiflu to relieve symtoms of the flu, and found that 572 experienced nausea. Use a 0.01 significance level to test the claim that the percentage of people who take Tamiflu for the relief of flu symtoms and experience nausea is greater than 30%.a) Identify the null and alternative hypotheses?�0: �1: b) What type of hypothesis test should you conduct (left-, right-, or two-tailed)? left-tailed right-tailed two-tailed c) Identify the appropriate significance level.d) Calculate your test statistic. Write the result below, and be sure to round your final answer to two decimal…
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	Remission	No remission
NSAID use	182	227
No NSAID use	628	509