A certain disease-causing gene in humans is located on the short arm of chromosome 4, in band 6 within region 1.  Write the cytogenetic location of this gene from this information.

Q: Notably, one subunit of APC itself must remain phosphorylated at a single amino acid during sister…

A: In the phosphorylation reactions, proteins are reversibly modified. It is a regulatory reaction. The…

Q: a. In which sex, XY males or XX females, would the Sxl protein bind to the msl-2 mRNA? b. As…

A: Drosophila sex determination and dosage compensation are primarily controlled by two distinct sets…

Q: If the gene product is protein then why not to provide these protein from exogenous source to meet…

A: DNA undergoes transcription to form RNA which then undergoes translation to form DNA.

Q: Is the sequence of amino acids in rubisco encoded by nuclear genes or not? Explain.

A: The enzyme rubisco stands for ribulose bisphosphate carboxylase/oxygenase. It acts as a key enzyme…

Q: st noncoding RNA (ncRNA) triggers X inactivation by coating the X chromosome that produces it and by…

A: Xist is a long non-coding RNA on the X chromosome. Xist acronym is X -inactive-specific transcript…

Q: Prader-Willi syndrome and Angelman syndrome

A: Genetic disorders: The inherited medical condition or disorder caused by a DNA abnormality is known…

Q: In tumor cells obtained from patients with Burkittlymphoma, a cancer of the immune system’s B…

A: Genetics is a branch of science that deals in the study of genes, heredity, and genetic variation of…

Q: When an injury occurs to the skin, the epithelial cells near the wound are signaled to react (by…

A: Introduction:- Chromosomes are the most condensed and compact structures that are made up of DNA…

Q: Which type/s of histones is/are not part of the histone octamer wrapped by DNA strands but is found…

A: Histones proteins are present as octamer (eight) complex at the center of nucleosome. It consist of…

Q: Although each cell in your body contains the same set of genes, the genes that are “turned on”…

A: DISCLAIMER FOR MULTIPLE   Since you have asked multiple question, we will solve the first question…

Q: “In an organism that reproduces asexually, there is no difference between a somatic cell mutation…

A: Somatic mutations These refers to the mutations in a single body cell, which cannot be inherited.…

Q: “DNMT3L Connects Unmethylated Lysine 4 of Histone H3 to de novo Methylation of DNA,” the authors…

A: Figure a and b of the paper “DNMT3L Connects Unmethylated Lysine 4 of Histone H3 to de novo…

Q: MSH2 is a gene commonly associated with HNPCC (Hereditary nonpolyposis colorectal cancer). This gene…

A: Hereditary nonpolyposis colorectal cancer (HNPCC), also known as Lynch syndrome, is an inherited…

Q: Insulin is a peptide hormone encoded by the INS gene, which is on chromosome 11. Insulin is produced…

A: The hormone insulin is required by the body to reduce the level of blood glucose. The pancreatic…

Q: Let’s suppose an X-linked gene in mice exists as two alleles, whichwe will call B and b.…

A: The females contain two copies of X chromosomes. These copies are derived from the maternal and…

Q: Following X-chromosome inactivation, most of the genes on theinactivated X chromosome are silenced.…

A: Females have two copies of the X chromosome, producing a double dose of X-linked genes. The…

Q: List the following steps of gene expression in eukaryotes in chronological order. Also indicate…

A: RNA processing refers to the series of events where the pre-mRNA is converted to mature RNA by…

Q: DNA methylation is considered an epigenetic phenomenon because the pattern of methylation can be…

A: Epigenetics is considered as a study of certain gene expressions, which is heritable.

Q: Given a mutation in the promoter, coding region, and/or non-coding region of a gene, explain how…

A: The mutation is a sudden heritable change in the genetic makeup of a cell which mostly results in…

Q: One of these is not part of the nucleosome core but is thought to participate in locking the two…

A: The fundamental subunit of chromatin is termed nucleosome. The nucleosome is made of two turns of…

Q: Base on your knowledge of DNA, chromosomes and epigenetics and upon examining the picture below,…

A: Epigenetic modification is the changes in chromatin structure which can result in repression or…

Q: Some cancers are consistently associated with the deletion of a particularpart of a chromosome. Does…

A: Proto-oncogenes are normal genes that encode for proteins required for the promotion of cell cycle.…

Q: Determine the correspondence of the gene X and gene Y to the mutant gene causing Trp-phenotype

A: An organism's genotype is influenced by its genome as well as by its environment. The physical…

Q: Explain how a loss-of-function allele in a gene encoding a cohesin protein could be dominant to…

A: Cornelia de Lange syndrome (CdLS) is a rare human disease caused by a dominant loss-of-function…

Q: Approximately how many copies of chromosome 2 are found in a polytene chromosome in Drosophila?

A: Polytene chromosomes are special type of chromosomes, which have thousands of DNA strands. They…

Q: In a mutant mouse, it was discovered that a gene "W" is moved from its original chromosomal locus to…

A: Introduction  A mutation is a change in the structure of a gene, which is the fundamental unit of…

Q: Determine the correspondence of the gene X and gene Y to the mutant gene causing Trp-phenotype

A: An organism's genotype is influenced by its genome as well as by its environment. The physical…

Q: Which of the following is most influenced by the SRY gene?

A: Introduction  Chromosomes are classified into two types: Autosomes and Allosomes/Sex chromosomes.…

Q: Which of the following scenarios will cause the maternal X chromosome to condense into a Barr body?…

A: The following scenarios will cause the maternal X chromosome to condense into a barr body:. Option 2…

Q: Explain how the Sxl promoter “counts” the number of Xchromosomes in Drosophila.

A: In Drosophila, male flies have only one X chromosome and female flies have two XX chromosomes.

Q: The HbβS(sickle-cell) allele of the human β-globingene changes the sixth amino acid in the…

A: Sickle cell anemia is a blood disorder in which an improper folding of hemoglobin occurs. In this…

Q: Describe two different ways that histone modifications may alter chromatin structure.

A: Chromosomes appear at the time of cell division in the form of thread like structures inside the…

Q: Gene A encodes for a protein A which prevents exit from the G1 phase of the cell cycle. You are…

A: Cancer is the uncontrolled cell division that is highly under the control of genes. Cell cycle is a…

Q: An old genetic observation is that a normally active gene will be silenced if it is moved by…

A: Histone alterations are linked to different transcription stages and functions, and epigenetic…

Q: Due to a nucleotide substitution, the fourth residue of H3 in a specific tissue cell of an organism…

A: Protein domains are the structural units of protein that are responsible for specific function of…

Genomic studies

Genomic studies (genomics) is the study of the whole genome of an organism. Using bioinformatics and high-performance computing, genomic researchers examined massive amounts of deoxyribonucleic acid (DNA)-sequence data to discover variations or mutations that affect drug response, health, or disease. Genomics is a much younger discipline than genetics, having only emerged in the last few decades as a result of technological advancements in DNA sequencing and computational biology.