(a) A retrovirus inserts its RNA into the cel: the wiral RNA undergoes Viral RNA reverse transcription and inserts into the host chromosome nest to a protooncogene. Reverse transcription Host chromosome Provirus Proto oncogene Viral reproduction When the virus reproduces, the proto-oncogene is incorporated into the virus In repeated rounds of viral infection and Repeated rounds of infection and reproduction, the proto-oncogene becomes rearranged or mutated or both. reproduction Viral RNA Reverse transcription producing an oncogene that inserted back into the hast chromosome. Host chromosome Mutation Provirus Oncogene (b) A retrovirus infects a cell... 2.and the provirus 3 The strong viral promoter stimulates over- expression of the inserts near a proto-oncogene. proto-oncogene. Strong viral promoter Provirus / Proto-oncogene Over- expression MRNA 23.14 Retroviruses can cause cancer by (a) mutating or rearranging proto- oncogenes or (b) inserting strong promoters near proto-oncogenes.
(a) A retrovirus inserts its RNA into the cel: the wiral RNA undergoes Viral RNA reverse transcription and inserts into the host chromosome nest to a protooncogene. Reverse transcription Host chromosome Provirus Proto oncogene Viral reproduction When the virus reproduces, the proto-oncogene is incorporated into the virus In repeated rounds of viral infection and Repeated rounds of infection and reproduction, the proto-oncogene becomes rearranged or mutated or both. reproduction Viral RNA Reverse transcription producing an oncogene that inserted back into the hast chromosome. Host chromosome Mutation Provirus Oncogene (b) A retrovirus infects a cell... 2.and the provirus 3 The strong viral promoter stimulates over- expression of the inserts near a proto-oncogene. proto-oncogene. Strong viral promoter Provirus / Proto-oncogene Over- expression MRNA 23.14 Retroviruses can cause cancer by (a) mutating or rearranging proto- oncogenes or (b) inserting strong promoters near proto-oncogenes.
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
Related questions
Question
Assume that the provirus in Figure 23.14 inserts just upstream of a
tumor-suppressor gene. Would this insertion be likely to cause cancer?
Why or why not?
Expert Solution
This question has been solved!
Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.
This is a popular solution!
Trending now
This is a popular solution!
Step by step
Solved in 2 steps
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Recommended textbooks for you
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:
9780134580999
Author:
Elaine N. Marieb, Katja N. Hoehn
Publisher:
PEARSON
Biology 2e
Biology
ISBN:
9781947172517
Author:
Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:
OpenStax
Anatomy & Physiology
Biology
ISBN:
9781259398629
Author:
McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:
Mcgraw Hill Education,
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:
9780134580999
Author:
Elaine N. Marieb, Katja N. Hoehn
Publisher:
PEARSON
Biology 2e
Biology
ISBN:
9781947172517
Author:
Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:
OpenStax
Anatomy & Physiology
Biology
ISBN:
9781259398629
Author:
McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:
Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:
9780815344322
Author:
Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:
W. W. Norton & Company
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:
9781260159363
Author:
Martin, Terry R., Prentice-craver, Cynthia
Publisher:
McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)
Biology
ISBN:
9781260231700
Author:
Sylvia S. Mader, Michael Windelspecht
Publisher:
McGraw Hill Education