7. Warfarin is a blood thinner known by its tradename Coumadin. Warfarin has a formula mass of 308.33 g/mol and a pka of 5.0. Sun et al (J. Pharm. Biomed. Anal. (2006) 42, 218-222) reported a plasma concentration of 567.6 ng/ml. (1.84 uM) warfarin in patients within one month of heart valve treatment. Blood pH is 24. What percent of warfarin in the plasma is not deprotonated? The body has 5.0L of blood.

7. Warfarin is a blood thinner known by its tradename Coumadin. Warfarin has a formula mass of 308.33 g/mol and a pka of 5.0. Sun et al (J. Pharm. Biomed. Anal. (2006) 42, 218-222) reported a plasma concentration of 567.6 ng/ml. (1.84 uM) warfarin in patients within one month of heart valve treatment. Blood pH is 24. What percent of warfarin in the plasma is not deprotonated? The body has 5.0L of blood.

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

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Concept explainers

Solutions

Solutions can be considered as homogeneous mixtures which contain two or more than two chemical substances. The chemical substance which is the greater part is defined as solvent. And the chemical substance that is dissolved in a solvent is referred to as solute. Solution chemistry plays an important role in chemistry since it supports many commercial applications of solutions.

Question

7. Warfarin is a blood thinner known by its tradename Coumadin. Warfarin has a formula mass of 308.33 g/mol and a pka of 5.0. Sun
et al (J. Pharm. Biomed. Anal. (2006) 42, 218-222) reported a plasma concentration of 567.6 ng/ml. (1.84 uM) warfarin in patients
within one month of heart valve treatment. Blood pH is Z4. What percent of warfarin in the plasma is not deprotonated? The body
has 5.0L of blood.
но
22, warfarin

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