7. Warfarin is a blood thinner known by its tradename Coumadin. Warfarin has a formula mass of 308.33 g/mol and a pka of 5.0. Sun et al (J. Pharm. Biomed. Anal. (2006) 42, 218-222) reported a plasma concentration of 567.6 ng/ml. (1.84 uM) warfarin in patients within one month of heart valve treatment. Blood pH is 24. What percent of warfarin in the plasma is not deprotonated? The body has 5.0L of blood.
7. Warfarin is a blood thinner known by its tradename Coumadin. Warfarin has a formula mass of 308.33 g/mol and a pka of 5.0. Sun et al (J. Pharm. Biomed. Anal. (2006) 42, 218-222) reported a plasma concentration of 567.6 ng/ml. (1.84 uM) warfarin in patients within one month of heart valve treatment. Blood pH is 24. What percent of warfarin in the plasma is not deprotonated? The body has 5.0L of blood.
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
Related questions
Question
![7. Warfarin is a blood thinner known by its tradename Coumadin. Warfarin has a formula mass of 308.33 g/mol and a pka of 5.0. Sun
et al (J. Pharm. Biomed. Anal. (2006) 42, 218-222) reported a plasma concentration of 567.6 ng/ml. (1.84 uM) warfarin in patients
within one month of heart valve treatment. Blood pH is Z4. What percent of warfarin in the plasma is not deprotonated? The body
has 5.0L of blood.
но
22, warfarin](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Fd6e57534-170a-49bd-96e4-9e2568b97eb1%2Fb5ecd583-e363-465d-8390-1b56e04b2db2%2Falq8ebn_processed.jpeg&w=3840&q=75)
Transcribed Image Text:7. Warfarin is a blood thinner known by its tradename Coumadin. Warfarin has a formula mass of 308.33 g/mol and a pka of 5.0. Sun
et al (J. Pharm. Biomed. Anal. (2006) 42, 218-222) reported a plasma concentration of 567.6 ng/ml. (1.84 uM) warfarin in patients
within one month of heart valve treatment. Blood pH is Z4. What percent of warfarin in the plasma is not deprotonated? The body
has 5.0L of blood.
но
22, warfarin
Expert Solution
![](/static/compass_v2/shared-icons/check-mark.png)
This question has been solved!
Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.
Step by step
Solved in 5 steps
![Blurred answer](/static/compass_v2/solution-images/blurred-answer.jpg)
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.Recommended textbooks for you
![Chemistry](https://www.bartleby.com/isbn_cover_images/9781305957404/9781305957404_smallCoverImage.gif)
Chemistry
Chemistry
ISBN:
9781305957404
Author:
Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:
Cengage Learning
![Chemistry](https://www.bartleby.com/isbn_cover_images/9781259911156/9781259911156_smallCoverImage.gif)
Chemistry
Chemistry
ISBN:
9781259911156
Author:
Raymond Chang Dr., Jason Overby Professor
Publisher:
McGraw-Hill Education
![Principles of Instrumental Analysis](https://www.bartleby.com/isbn_cover_images/9781305577213/9781305577213_smallCoverImage.gif)
Principles of Instrumental Analysis
Chemistry
ISBN:
9781305577213
Author:
Douglas A. Skoog, F. James Holler, Stanley R. Crouch
Publisher:
Cengage Learning
![Chemistry](https://www.bartleby.com/isbn_cover_images/9781305957404/9781305957404_smallCoverImage.gif)
Chemistry
Chemistry
ISBN:
9781305957404
Author:
Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:
Cengage Learning
![Chemistry](https://www.bartleby.com/isbn_cover_images/9781259911156/9781259911156_smallCoverImage.gif)
Chemistry
Chemistry
ISBN:
9781259911156
Author:
Raymond Chang Dr., Jason Overby Professor
Publisher:
McGraw-Hill Education
![Principles of Instrumental Analysis](https://www.bartleby.com/isbn_cover_images/9781305577213/9781305577213_smallCoverImage.gif)
Principles of Instrumental Analysis
Chemistry
ISBN:
9781305577213
Author:
Douglas A. Skoog, F. James Holler, Stanley R. Crouch
Publisher:
Cengage Learning
![Organic Chemistry](https://www.bartleby.com/isbn_cover_images/9780078021558/9780078021558_smallCoverImage.gif)
Organic Chemistry
Chemistry
ISBN:
9780078021558
Author:
Janice Gorzynski Smith Dr.
Publisher:
McGraw-Hill Education
![Chemistry: Principles and Reactions](https://www.bartleby.com/isbn_cover_images/9781305079373/9781305079373_smallCoverImage.gif)
Chemistry: Principles and Reactions
Chemistry
ISBN:
9781305079373
Author:
William L. Masterton, Cecile N. Hurley
Publisher:
Cengage Learning
![Elementary Principles of Chemical Processes, Bind…](https://www.bartleby.com/isbn_cover_images/9781118431221/9781118431221_smallCoverImage.gif)
Elementary Principles of Chemical Processes, Bind…
Chemistry
ISBN:
9781118431221
Author:
Richard M. Felder, Ronald W. Rousseau, Lisa G. Bullard
Publisher:
WILEY