4. How will glycogen levels most likely be affected in patients with a GK mutation? a. Elevated in muscle, reduced in liver b. Elevated in muscle, elevated in liver c. Unaffected in muscle, reduced in liver d. Unaffected in muscle, elevated in liver

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Patients with a form of early-onset diabetes were found to carry a variety of mutations reducing the function of the
glucokinase (GK) enzyme. These patients are heterozygous for one of the mutations, and thus show only partial
rather than complete loss of GK activity. Answer the following questions about these patients.
How would blood sugar lovolc likoly bo affoctod in CK nautatie
Transcribed Image Text:Patients with a form of early-onset diabetes were found to carry a variety of mutations reducing the function of the glucokinase (GK) enzyme. These patients are heterozygous for one of the mutations, and thus show only partial rather than complete loss of GK activity. Answer the following questions about these patients. How would blood sugar lovolc likoly bo affoctod in CK nautatie
4. How will glycogen levels most likely be affected in patients with a GK mutation?
a. Elevated in muscle, reduced in liver
b. Elevated in muscle, elevated in liver
c. Unaffected in muscle, reduced in liver
d. Unaffected in muscle, elevated in liver
Transcribed Image Text:4. How will glycogen levels most likely be affected in patients with a GK mutation? a. Elevated in muscle, reduced in liver b. Elevated in muscle, elevated in liver c. Unaffected in muscle, reduced in liver d. Unaffected in muscle, elevated in liver
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