4. Briefly list three mechanisms by which monoclonal antibodies that bind to tumor surface antigens, such as anti-CD20, cause killing of tumor cells.
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Briefly list three mechanisms by which monoclonal antibodies that bind to tumor
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- How can the molecular analysis ofan individual tumor be more effectivelyused to design effective therapies tokill it?1. ALT is not used as a hepatocellular damage marker in cattle. Explain why.Link: Lack of RAC1 in macrophages protects against atherosclerosis - PMC (nih.gov) Could you explain the relationship between plaque, macrophages, RAC1, SM22 and smooth muslce cells? Would like to understand this topic below a bit better and the effects these things have on each other. After discovering that advanced plaques had a greater macrophage RAC1 expression than intermediate plaques, immunofluorescence was used to stain human intermediate (type III) and advanced (type VI) atherosclerotic plaques. The anti-Mac-2 (Cedarlane) antibody was used to identify macrophages, while the RAC1 (Sigma-Aldrich) and SM22 (Abcam) antibodies were used to identify smooth muscle cells.
- 1. "Which of the following statements is/are true? The only region in the body where a virus‐infected cell can interact with T cells is in the lymph nodes.Virion surface proteins tend to elicit a stronger immune response during the course of natural infection than do internal components of the virion.Epitope‐containing antigens must be digested to single amino acids and reassembled at the surface in the presence of histocompatibility antigens in order to provoke immunity. 2. Why are soluble antibodies (the products of the humoral response) good antiviral agents? 3. What are the roles of the following cells in the vertebrate immune response? B cellsHelper T cells (CD4+)Cytotoxic T cells (CD8+)"21. Which of the following can lead to cancer development? a. viruses b. mutation in cyclin production c. differentiated stem cells d. AIDS e. all of the above except c 22. Your patient is born without B cells. He cannot a. fight off intracellular infections b. have a Type IV hypersensitivity reaction c. fight off extracellular infections d. destroy microorganisms through alternate complement e. c & d 23. Extensive vomiting can lead to alkalosis due to -a. continued excretion of HCO3 b. accumulation of potassium c. emphysema d. a high protein diet e. increased renin production 24. Which of the following could lead to renal osteodystrophy? a. low levels of parathyroid hormone b. high levels of blood calcium c. injections of calcitrol d. increased physical activity e. a high protein diet 25. Which of the following can cause diarrhon?Pls help