4. (a) here were collected from a blood analysis for a l-month-old. Which citrate cycle enzyme is defective in this patient? Explain your reasoning. Defects in the citrate cycle are rare but have been described. The data in the table shown Patient (mM/L) 25.5 + 1.2 Control (mM/L) Compound Lactate 1.5 ± 0.3 Fumarate 7.1 ±0.5 < 0.1 Succinate 10.0 ± 1.0 <0.1 0.5 ± 0.2 Malate 4.2 ±0.4 Citrate 5.5 + 1.5 150 ± 25

4. (a) here were collected from a blood analysis for a l-month-old. Which citrate cycle enzyme is defective in this patient? Explain your reasoning. Defects in the citrate cycle are rare but have been described. The data in the table shown Patient (mM/L) 25.5 + 1.2 Control (mM/L) Compound Lactate 1.5 ± 0.3 Fumarate 7.1 ±0.5 < 0.1 Succinate 10.0 ± 1.0 <0.1 0.5 ± 0.2 Malate 4.2 ±0.4 Citrate 5.5 + 1.5 150 ± 25

Biochemistry

6th Edition

ISBN:9781305577206

Author:Reginald H. Garrett, Charles M. Grisham

Publisher:Reginald H. Garrett, Charles M. Grisham

Chapter18: Glycolysis

Section: Chapter Questions

Problem 20P: Understanding the Mechanism of Hemolytic Anemia Genetic defects in glycolytic enzymes can have...

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