4) (2 pts.) This is a "retrosynthesis" problem. Identify the TWO MOLECULES necessary to prepare theamine shown below via reductive amination.CN-CH₂N.CH3

Step 1:Two ways are possible 1) way with one molecule 2) way two molecules Step 2:Answer is 2) way…

Answered: 4) (2 pts.) This is a "retrosynthesis"…

Organic Chemistry: A Guided Inquiry

2nd Edition

ISBN:9780618974122

Author:Andrei Straumanis

Publisher:Andrei Straumanis

Chapter23: Addition To A Carbonyl

Section: Chapter Questions

Problem 25E

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4) This is a "retrosynthesis" problem. Identify the TWO MOLECULES necessary to amine shown below via reductive amination. a NH
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3. For the following amines, propose a stepwise synthesis for each compound. ? a) b) ? OH ZH NH₂ 4. Imidazole has two nitrogen atoms, labeled as N3 and N1. Please indicate which nitrogen is more basic, Draw the products of protonating both nitrogen atoms and
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Following are structural formulas for amphetamine and methamphetamine. H NH, CH3 (a) (b) Amphetamine (racemic) Methamphetamine (racemic) The major central nervous system effects of amphetamine and amphetamine-like drugs are locomotor stimulation, euphoria and excitement, stereotyped behavior, and anorexia. Show how each drug can be synthesized by reductive amination of an ap- propriate aldehyde or ketone and amine.
(d) When a primary amine is combined with a ketone, both an imine and an enamine can be obtained. With most ketones, the major product is the imine, as shown: H3C NH2 -N -CH3 -CH3 imine: major product enamine: minor product However, in some cases, like the one shown below, the major product is the enamine. CO₂Et CO₂Et CO₂Et H H3C NH2 -CH3 imine: minor product -CH3 enamine: major product Referring to specific features of the starting materials, intermediates, or products, explain why.
Several additional amine syntheses are effectively limited to making primary amines. The reduction of azides and nitrocompounds and the Gabriel synthesis leave the carbon chain unchanged. Formation and reduction of a nitrile adds onecarbon atom. Show how these amine syntheses can be used for the following conversions.(a) allyl bromide S allylamine (b) ethylbenzene S p@ethylaniline
4. Propose a synthesis scheme for the amine shown below using the starting material indicated. No mechanisms (electron flow arrows, etc.) are needed! (More than one reaction will be needed to make this amine.) Make: From: NH, and other reagents/reactants

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4) (2 pts.) This is a "retrosynthesis" problem. Identify the TWO MOLECULES necessary to prepare the amine shown below via reductive amination. CN-CH₂ N. CH3