3.Tris(hydroxymethyl)aminomethane [(HOCH2)3CNH2-Tris or THAM] is a weak base frequently used to prepare buffers in biochemistry. Its Kb is 1.2 x 10^-6 and pKb is 5.92. The corresponding pKa is 8.08, which is near the pH of the physiological buffers, and so it exhibits good buffering capacity at physiological pH. What weight of THAM must be taken with 100 mL of 0.50 M HCl to prepare 1L of a pH 7.90 buffer?

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3.Tris(hydroxymethyl)aminomethane [(HOCH2)3CNH2-Tris or
THAM] is a weak base frequently used to prepare buffers in
biochemistry. Its Kb is 1.2 x 10^-6 and pKb is 5.92. The
corresponding pKa is 8.08, which is near the pH of the
physiological buffers, and so it exhibits good buffering capacity at
physiological pH. What weight of THAM must be taken with 100
mL of 0.50 M HCl to prepare 1L of a pH 7.90 buffer?
g
Transcribed Image Text:3.Tris(hydroxymethyl)aminomethane [(HOCH2)3CNH2-Tris or THAM] is a weak base frequently used to prepare buffers in biochemistry. Its Kb is 1.2 x 10^-6 and pKb is 5.92. The corresponding pKa is 8.08, which is near the pH of the physiological buffers, and so it exhibits good buffering capacity at physiological pH. What weight of THAM must be taken with 100 mL of 0.50 M HCl to prepare 1L of a pH 7.90 buffer? g
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