As a technician in a large pharmaceutical research firm, you need to produce 450. mL of a potassium dihydrogen phosphate buffer solution of pH = 7.09. The pK, of H₂PO4 is 7.21. You have the following supplies: 2.00 L of 1.00 M KH₂PO4 stock solution, 1.50 L of 1.00 MK₂HPO4 stock solution, and a carboy of pure distilled H₂O. How much 1.00 M KH₂PO4 will you need to make this solution? (Assume additive volumes.) Express your answer to three significant digits with the appropriate units. ▸ View Available Hint(s) Volume of KH₂PO4 needed = 171 Submit Previous Answers HÅ mL

Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
icon
Related questions
Question
The Henderson-Hasselbalch equation relates the pH of a buffer
solution to the pKa of its conjugate acid and the ratio of the
concentrations of the conjugate base and acid. The equation is
important in laboratory work that makes use of buffered solutions, in
industrial processes where pH needs to be controlled, and in
medicine, where understanding the Henderson-Hasselbalch equation
is critical for the control of blood pH.
As a technician in a large pharmaceutical research firm, you need to produce 450. mL of a potassium dihydrogen phosphate buffer solution of pH = 7.09. The pKa of
H₂PO4 is 7.21. You have the following supplies: 2.00 L of 1.00 M KH₂PO4 stock solution, 1.50 L of 1.00 M K₂HPO4 stock solution, and a carboy of pure distilled
H₂O.
How much 1.00 M KH₂PO4 will you need to make this solution? (Assume additive volumes.)
Express your answer to three significant digits with the appropriate units.
► View Available Hint(s)
Volume of KH₂PO4 needed = 171
Submit
Previous Answers
μA
X Incorrect; Try Again; One attempt remaining
mL
Review | Constants | Periodic Table
?
Transcribed Image Text:The Henderson-Hasselbalch equation relates the pH of a buffer solution to the pKa of its conjugate acid and the ratio of the concentrations of the conjugate base and acid. The equation is important in laboratory work that makes use of buffered solutions, in industrial processes where pH needs to be controlled, and in medicine, where understanding the Henderson-Hasselbalch equation is critical for the control of blood pH. As a technician in a large pharmaceutical research firm, you need to produce 450. mL of a potassium dihydrogen phosphate buffer solution of pH = 7.09. The pKa of H₂PO4 is 7.21. You have the following supplies: 2.00 L of 1.00 M KH₂PO4 stock solution, 1.50 L of 1.00 M K₂HPO4 stock solution, and a carboy of pure distilled H₂O. How much 1.00 M KH₂PO4 will you need to make this solution? (Assume additive volumes.) Express your answer to three significant digits with the appropriate units. ► View Available Hint(s) Volume of KH₂PO4 needed = 171 Submit Previous Answers μA X Incorrect; Try Again; One attempt remaining mL Review | Constants | Periodic Table ?
Expert Solution
steps

Step by step

Solved in 2 steps with 2 images

Blurred answer
Knowledge Booster
Acid-Base Titrations
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.
Similar questions
  • SEE MORE QUESTIONS
Recommended textbooks for you
Chemistry
Chemistry
Chemistry
ISBN:
9781305957404
Author:
Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:
Cengage Learning
Chemistry
Chemistry
Chemistry
ISBN:
9781259911156
Author:
Raymond Chang Dr., Jason Overby Professor
Publisher:
McGraw-Hill Education
Principles of Instrumental Analysis
Principles of Instrumental Analysis
Chemistry
ISBN:
9781305577213
Author:
Douglas A. Skoog, F. James Holler, Stanley R. Crouch
Publisher:
Cengage Learning
Organic Chemistry
Organic Chemistry
Chemistry
ISBN:
9780078021558
Author:
Janice Gorzynski Smith Dr.
Publisher:
McGraw-Hill Education
Chemistry: Principles and Reactions
Chemistry: Principles and Reactions
Chemistry
ISBN:
9781305079373
Author:
William L. Masterton, Cecile N. Hurley
Publisher:
Cengage Learning
Elementary Principles of Chemical Processes, Bind…
Elementary Principles of Chemical Processes, Bind…
Chemistry
ISBN:
9781118431221
Author:
Richard M. Felder, Ronald W. Rousseau, Lisa G. Bullard
Publisher:
WILEY