3.2. Consider the reversible product-formation reaction in an enzyme-catalyzed bioreaction: k k2 E+S(ES) E+P k_2 Develop a rate expression for product-formation using the quasi-steady-state approximation and show that
3.2. Consider the reversible product-formation reaction in an enzyme-catalyzed bioreaction: k k2 E+S(ES) E+P k_2 Develop a rate expression for product-formation using the quasi-steady-state approximation and show that
Introduction to Chemical Engineering Thermodynamics
8th Edition
ISBN:9781259696527
Author:J.M. Smith Termodinamica en ingenieria quimica, Hendrick C Van Ness, Michael Abbott, Mark Swihart
Publisher:J.M. Smith Termodinamica en ingenieria quimica, Hendrick C Van Ness, Michael Abbott, Mark Swihart
Chapter1: Introduction
Section: Chapter Questions
Problem 1.1P
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![3.2. Consider the reversible product-formation reaction in an enzyme-catalyzed bioreaction:
E+S:
(ES) E+P
Develop a rate expression for product-formation using the quasi-steady-state approximation and show
that
d[P] _ (v,/K„)[S]-(v,/K,)[P]
% =
dt
[S] ¸ [P]
1+
+
K m K,
k+k2
and V, = k,[E,], V, =k¬[E,].
k_2
where Km
k+k,
2 and Kp
k,](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F0872c6df-fb2c-4517-a5c1-ab22543d5d2b%2F4ecf3ae4-2fa0-479c-b466-d47220120398%2Frehkbkk_processed.png&w=3840&q=75)
Transcribed Image Text:3.2. Consider the reversible product-formation reaction in an enzyme-catalyzed bioreaction:
E+S:
(ES) E+P
Develop a rate expression for product-formation using the quasi-steady-state approximation and show
that
d[P] _ (v,/K„)[S]-(v,/K,)[P]
% =
dt
[S] ¸ [P]
1+
+
K m K,
k+k2
and V, = k,[E,], V, =k¬[E,].
k_2
where Km
k+k,
2 and Kp
k,
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