biochemistry 3. When the hormone vasopressin stimulates cleavage of phosphatidylinositol 4,5-bisphophate(PIP2) by phospholipase C, two products are formed.a) The structure of inositol is shown at right. Use your knowledge ofnaming conventions to determine the structure of PIP2. Explain in HOcomplete sentences which groups would be attached to thisinositol in phosphatidylinositol 4,5-bisphophate (PIP2).OHHOWHO""HO,OHb) Given the information below and your knowledge of glycerophospholipids, what are thetwo products of cleavage by phospholipase C?Phospholipase Site of cleavageEster bond at C-1 of glycerolEster bond at C-2 of glycerolPhosphodiester bond at C-3 of glycerolPhosphodiester bond between phosphate and head groupA1A2Cc) Compare the properties and solubility of these two products. Predict whether eitherwould diffuse readily through the cytosol.

The hormone vasopressin when binds to the ligand it activates cellular signaling, which involves the…

3. When the hormone vasopressin stimulates cleavage of phosphatidylinositol 4,5-bisphophate (PIP2) by phospholipase C, two products are formed. a) The structure of inositol is shown at right. Use your knowledge of naming conventions to determine the structure of PIP2. Explain in HO complete sentences which groups would be attached to this inositol in phosphatidylinositol 4,5-bisphophate (PIP2). OH HOW HO O., он b) Given the information below and your knowledge of glycerophospholipids, what are the two products of cleavage by phospholipase C? Phospholipase Site of cleavage A1 Ester bond at C-1 of glycerol Ester bond at C-2 of glycerol Phosphodiester bond at C-3 of glycerol Phosphodiester bond between phosphate and head group A2 c) Compare the properties and solubility of these two products. Predict whether either would diffuse readily through the cytosol.

3. When the hormone vasopressin stimulates cleavage of phosphatidylinositol 4,5-bisphophate (PIP2) by phospholipase C, two products are formed. a) The structure of inositol is shown at right. Use your knowledge of naming conventions to determine the structure of PIP2. Explain in HO complete sentences which groups would be attached to this inositol in phosphatidylinositol 4,5-bisphophate (PIP2). OH HOW HO O., он b) Given the information below and your knowledge of glycerophospholipids, what are the two products of cleavage by phospholipase C? Phospholipase Site of cleavage A1 Ester bond at C-1 of glycerol Ester bond at C-2 of glycerol Phosphodiester bond at C-3 of glycerol Phosphodiester bond between phosphate and head group A2 c) Compare the properties and solubility of these two products. Predict whether either would diffuse readily through the cytosol.

Biochemistry

6th Edition

ISBN:9781305577206

Author:Reginald H. Garrett, Charles M. Grisham

Publisher:Reginald H. Garrett, Charles M. Grisham

Chapter24: Lipid Biosynthesis

Section: Chapter Questions

Problem 20P

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