3. Make it happen Your friend claims the reaction below can occur via Claisen condensation. 3.1. Explain using words and drawings-why this transformation cannot proceed as written, focusing on mechanism. Then, draw the actual expected product(s) of a Claisen condensation between acetyl CoA and propionyl CoA (shown below). SCOA Explanation + acetyl-Co A acetyltransferase (Class 2) SCOA + COASH Actual expected product(s) SCOA 3.2. Propose a series of reactions that can successfully accomplish this transformation using tools from our metabolic toolbox. For each step in your pathway, name or draw the reagents/cofactors required and draw compound structures/products. You do not need to show electron pushing mechanisms.
3. Make it happen Your friend claims the reaction below can occur via Claisen condensation. 3.1. Explain using words and drawings-why this transformation cannot proceed as written, focusing on mechanism. Then, draw the actual expected product(s) of a Claisen condensation between acetyl CoA and propionyl CoA (shown below). SCOA Explanation + acetyl-Co A acetyltransferase (Class 2) SCOA + COASH Actual expected product(s) SCOA 3.2. Propose a series of reactions that can successfully accomplish this transformation using tools from our metabolic toolbox. For each step in your pathway, name or draw the reagents/cofactors required and draw compound structures/products. You do not need to show electron pushing mechanisms.
Chapter22: Carbonyl Alpha-substitution Reactions
Section22.SE: Something Extra
Problem 20MP
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Transcribed Image Text:3. Make it happen
Your friend claims the reaction below can occur via Claisen condensation.
3.1. Explain using words and drawings-why this transformation cannot proceed as written, focusing
on mechanism. Then, draw the actual expected product(s) of a Claisen condensation between acetyl
CoA and propionyl CoA (shown below).
SCOA
Explanation
+
acetyl-Co A acetyltransferase
(Class 2)
SCOA
+
COASH
Actual expected product(s)
SCOA
3.2. Propose a series of reactions that can successfully accomplish this transformation using tools from
our metabolic toolbox. For each step in your pathway, name or draw the reagents/cofactors required
and draw compound structures/products. You do not need to show electron pushing mechanisms.
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