3. Double-stranded breaks are potentially lethal, unless they are repaired. 4. Repair systems in the cell correct the double-stranded breaks by joining bro- ken ends back together (see Chapter 16 for a detailed discussion of DNA repair). FIGURE 17-19 Each of the four types of chromosomal rearrangements can be produced by either of two basic mechanisms: chromosome breakage and rejoining or crossing over between repetitive DNA. Chromosome regions are numbered 1 through 10. Homologous 5. If the two ends of the same break are rejoined, the original DNA order is re- stored. If the ends of two different breaks are joined, however, one result is one or another type of chromosomal rearrangement. 6. The only chromosomal rearrangements that survive meiosis are those that produce DNA molecules that have one centromere and two telomeres. If a chromosomes are the same color. Origins of chromosomal rearrangements Breakage and rejoining Crossing over between repetitive DNA Deletion -3 2 Loss 32 4 Loss Deletion and duplication 3 4 23 23 4 Inversion ! 10 10 Translocation 10 6 2 Chromosome break - Joining of broken ends Repetitive DNA segments X Crossover

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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In Figure 17-19, is there any difference between the inversion products formed from breakage and those
formed from crossing over?

3. Double-stranded breaks are potentially lethal, unless they are repaired.
4. Repair systems in the cell correct the double-stranded breaks by joining bro-
ken ends back together (see Chapter 16 for a detailed discussion of DNA repair).
FIGURE 17-19 Each of the four types
of chromosomal rearrangements can be
produced by either of two basic
mechanisms: chromosome breakage and
rejoining or crossing over between
repetitive DNA. Chromosome regions are
numbered 1 through 10. Homologous
5. If the two ends of the same break are rejoined, the original DNA order is re-
stored. If the ends of two different breaks are joined, however, one result is one or
another type of chromosomal rearrangement.
6. The only chromosomal rearrangements that survive meiosis are those that
produce DNA molecules that have one centromere and two telomeres. If a
chromosomes are the same color.
Origins of chromosomal rearrangements
Breakage and rejoining
Crossing over between repetitive DNA
Deletion
-3 2
Loss
32 4
Loss
Deletion
and
duplication
3
4
23
23
4
Inversion
! 10
10
Translocation
10
6
2 Chromosome break
- Joining of broken ends
Repetitive DNA segments
X Crossover
Transcribed Image Text:3. Double-stranded breaks are potentially lethal, unless they are repaired. 4. Repair systems in the cell correct the double-stranded breaks by joining bro- ken ends back together (see Chapter 16 for a detailed discussion of DNA repair). FIGURE 17-19 Each of the four types of chromosomal rearrangements can be produced by either of two basic mechanisms: chromosome breakage and rejoining or crossing over between repetitive DNA. Chromosome regions are numbered 1 through 10. Homologous 5. If the two ends of the same break are rejoined, the original DNA order is re- stored. If the ends of two different breaks are joined, however, one result is one or another type of chromosomal rearrangement. 6. The only chromosomal rearrangements that survive meiosis are those that produce DNA molecules that have one centromere and two telomeres. If a chromosomes are the same color. Origins of chromosomal rearrangements Breakage and rejoining Crossing over between repetitive DNA Deletion -3 2 Loss 32 4 Loss Deletion and duplication 3 4 23 23 4 Inversion ! 10 10 Translocation 10 6 2 Chromosome break - Joining of broken ends Repetitive DNA segments X Crossover
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