Answered: Why are people with balanced…

Why are people with balanced chromosomal translocations phenotypically normal? Do they suffer from reduced fertility? Why?

Human Biology (MindTap Course List)

11th Edition

ISBN:9781305112100

Author:Cecie Starr, Beverly McMillan

Publisher:Cecie Starr, Beverly McMillan

Chapter20: Chromosomes And Human Genetics

Section: Chapter Questions

Problem 2CT: Human sex chromosomes are XX for females and XY for males. a. With respect to an X-linked gene, how...

See similar textbooks

Related questions

Q: How can epistasis explain incomplete penetrance?

A: Penetrance in genetic terms refers to the ratio of individuals that carry a specific allele of a…

Q: What is Extrachromosomal inheritance?

A: Inheritance is the process by which this genetic information present in the genes is passed on from…

Q: Explain the causes of familial Down syndrome. How does it differ from Down syndrome due to…

A: Down syndrome is a disorder in which individuals have an extra copy of chromosome 21 instead of two…

Q: What are twins?Genetically what are the twotypes of twins that can begenerated?

A: Pregnancy is also termed as gestation during which one or more offspring develop in the uterus of a…

Q: What are polytypic genes?

A: Genes are defined as the building blocks and the coded information that defines the complete physico…

Q: What is the relationship between non-disjunction, changes in chromosome number and miscarriage? Why…

A: Chromosome abnormalities are of 2 types viz. numerical, where an individual has abnormal number of…

Q: In a woman who is a carrier of a mutant OTC deficiency allele, her sons who receive the mutant…

A: An alteration in the ornithine transcarbamylase (OTC) gene results in the genetic disorder known as…

Q: Table 8.1 shows that Turner syndrome occurs when an individual inherits one X chromosome but lacks a…

A: Chromosomal deletion syndrome occurs when whole or part of chromosomes are missing. Turner Syndrome…

Q: What are choromosome theory of inheritence?

A: The Chromosomal Theory of inheritance was suggested by two scientists named Sutton and Boveri, which…

Q: Draw a Punnett square for the dihybrid cross. There are two known alleles of gene occupying a…

A: Dihybrid cross involves two genes in a cross. That's why the two traits are involved in this cross.

Q: Why do most cases of Down syndrome originate from the mother? And how is this linked to maternal age…

A: Down syndrome also called "trisomy 21" is a condition in which a child is born having an additional…

Q: How is Down syndrome caused?

A: Human genetic disorders are caused due to the absence or excess or abnormal arrangement of one or…

Q: Why must the carrier of a genetic disease be heterozygous?

A: Homozygous means a person carries two identical pair of the gene whereas heterozygous means the…

Q: What is meant by the term diploid? Which cells of the humanbody are diploid, and which cells are…

A: The ploidy term refers to the number of sets of the chromosomes. The euploidy refers to the…

Q: How to reduce chromosomal abnormalities?

A: Chromosomal abnormalities can be structural or numerical. A structural chromosomal abnormality means…

Q: What is the most common chromosomal disorder?

Q: What causes Extrachromosomal inheritance?

A: Inheritance or heredity is passing-on one trait form the parents to the progeny by either asexual or…

Q: Explain Loss of p53 function leads to genomic instability?

A: The TP53 gene provides instructions for making a protein called tumor protein p53 (p53). This…

Q: How is it that genetic abnormalities that include an extra Y chromosome do not have a severe…

A: Genetically all human males normally have a XY chromosome whereas the females have a XX pair. They…

Q: What is the meaning of term haploinsufficiency?

A: The gene is the basic physical and functional unit of heredity. Genes are made up of…

Q: Why are there so few Y-linked traits in humans?

A: The study of genetic variations, heredity, and genes is called genetics.

Question

Why are people with balanced chromosomal translocations phenotypically normal? Do they suffer from reduced fertility? Why?

Definition Definition Observable physical traits or characteristics of an organism, which are determined by its genetic makeup (genotype) as well as environmental factors. These traits can include anything from eye color or height to behavior or disease susceptibility. Understanding an organism's phenotype is important in fields such as genetics, medicine, and ecology.

Expert Solution

Introduction

Chromosomal translocations are genomic events in which either a part or the entire chromosome breaks free and attaches to another chromosome. It can lead to the creation of fusion genes, disruption of genes or regulatory sequences, and misregulation of genes. Chromosome translocations are linked to numerous cancers.

Step by step

Solved in 2 steps

SEE SOLUTION Check out a sample Q&A here

Knowledge Booster

Learn more about

Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.

Similar questions

How Chromosomal Rearrangements are Caused?
identify two main themes underlying the phenomena of chromosomal changes?
What is chromosomal mapping?
Though an individual with abberations such as Robertsonian translocation may be phenotypically normal, they can generate gametes through meiosis that have atypical organizations of chromosomes, resulting in recurrent fetal abnormalities or miscarriages. Why, despite these Robertsonian translocations, are affected cells still able to generate typical gametes through meiosis?
Human sex chromosomes are XX for females and XY for males. a. With respect to an X-linked gene, how many different types of gametes can a male produce? b. If a female is homozygous for an X-linked allele, how many different types of gametes can she produce with respect to this allele? c. If a female is heterozygous for an X-linked allele, how many different types of gametes can she produce with respect to this allele?
What is physically exchanged during crossing over?
Describe the chromosomal alterations and phenotype of cri du chat syndrome and Prader-Willi syndrome.
A normal mother has translocations on chromosomes 14:21. With respect to chromosomes 14:21, how many combinations of chromosomes are possible? How many gametes are viable? If the woman has children with an normal father, what is the probability that there is a daughter with Down Syndrome or a son with an unaffected phenotype?
a)What is the synaptonemal complex? b)Why are the X and Y chromosomes not considered homologous even though they recombine at the PAR region? c)What is unique about the Y chromosome?
A boy with Down syndrome (trisomy 21) has 46 chromosomes. One parent and his two older sisters have a normal phenotype, but each have 45 chromosomes. a)Explain how this is possible. b)How many chromosomes do you expect to see in karyotypes of the parents? c)What term best describes this kind of chromosome abnormality? d)What is the probability the next child of this couple will have a normal phenotype and have 46 chromosomes? Explain your answer.
Two phenotypically unaffected parents produce two children with familial Down syndrome. Regarding chromosome 14 and 21, what are the chromosomal composition of the parents?
A phenotypically normal woman has an abnormally structured chromosome 2, along with a normal homologue. She marries a phenotypically normal man with an abnormally structured chromosome 16 and a normal homologue. What is the probability of their child will have an abnormal chromosome 2 and 16? What is the probability that this child, having inherited both abnormal chromosomes, will now pass both abnormal chromosomes to its children?