3. A student administered ibuprofen to a lab mice orally. She would like to find out the amount of ibuprofen in blood plasma at a specific time using HPLC. The chromatographic peak areas after 2 hours, 4 hours, and 8 hours are 38.34, 20.5, and 14.95 respectively. What is the concentration of ibuprofen in the plasma at each aforementioned time? Below is the corresponding peak area of the 5 ibuprofen standards. Standard Concentration (mg/mL) Peak area 0.5 5.02 1.0 2.0 10.05 17.15 3.0 19.79 6.0 39.72
3. A student administered ibuprofen to a lab mice orally. She would like to find out the amount of ibuprofen in blood plasma at a specific time using HPLC. The chromatographic peak areas after 2 hours, 4 hours, and 8 hours are 38.34, 20.5, and 14.95 respectively. What is the concentration of ibuprofen in the plasma at each aforementioned time? Below is the corresponding peak area of the 5 ibuprofen standards. Standard Concentration (mg/mL) Peak area 0.5 5.02 1.0 2.0 10.05 17.15 3.0 19.79 6.0 39.72
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Question
![3. A student administered ibuprofen to a lab mice orally. She would like to find out
the amount of ibuprofen in blood plasma at a specific time using HPLC. The
chromatographic peak areas after 2 hours, 4 hours, and 8 hours are 38.34, 20.5,
and 14.95 respectively. What is the concentration of ibuprofen in the plasma at each
aforementioned time? Below is the corresponding peak area of the 5 ibuprofen
standards.
Standard Concentration (mg/mL)
Peak area
5.02
0.5
1.0
10.05
2.0
17.15
3.0
19.79
6.0
39.72](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F6bd06549-c4fe-44bd-9100-ce395fd7c800%2Ff621b7a7-7048-442a-bc61-07b8ed3e8a9e%2Fapgbye8k_processed.jpeg&w=3840&q=75)
Transcribed Image Text:3. A student administered ibuprofen to a lab mice orally. She would like to find out
the amount of ibuprofen in blood plasma at a specific time using HPLC. The
chromatographic peak areas after 2 hours, 4 hours, and 8 hours are 38.34, 20.5,
and 14.95 respectively. What is the concentration of ibuprofen in the plasma at each
aforementioned time? Below is the corresponding peak area of the 5 ibuprofen
standards.
Standard Concentration (mg/mL)
Peak area
5.02
0.5
1.0
10.05
2.0
17.15
3.0
19.79
6.0
39.72
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