Chromatography 1. External Standard Method A. Calculate the regression equation and the R-squared value. B. Calculate the concentration of cocaine found in the blood samples of the presidentiables. Which presidential candidate “reliably” tested positive for cocaine?
Chromatography 1. External Standard Method A. Calculate the regression equation and the R-squared value. B. Calculate the concentration of cocaine found in the blood samples of the presidentiables. Which presidential candidate “reliably” tested positive for cocaine?
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Chromatography
1. External Standard Method
A. Calculate the regression equation and the R-squared value.
B. Calculate the concentration of cocaine found in the blood samples of the presidentiables. Which presidential candidate “reliably” tested positive for cocaine?
2. Internal Standard Method
>Calculate the concentration of party drug X in the blood samples of the presidential candidates.
>Suppose the LOD for party drug X is 0.200 ppm, which of the presidential candidates “reliably” tested for party drug X?
Transcribed Image Text:TLA: Chromatography
Instructions: Answer the following questions. Upload your solutions in the section provided in
the Google Classroom.
1. External Standard Method. Presidential candidates in Country X present themselves
for drug tests to belie each other's allegations of being a drug addict. Suppose the limit
of detection (minimum quantifiable amount that is reliable) of an HPLC instrument is
0.050 ppm (Meaning, a result below 0.050 ppm is not necessarily reliable or does not
necessarily give a positive result). The analyte to be measured is cocaine due to the
allegations provided by the current president of one presidential candidate being a
cocaine addict. Therefore, standard solutions of cocaine are prepared. The peak areas
for the cocaine standards are provided below.
Cocaine Standards (ppm)
Peak Area
0.050
0.0125
0.100
0.0259
0.500
0.1050
1.000
0.2000
5.000
0.9890
10.000
1.905
The presidentiables are given the freedom to use usernames for their results. The results for the
presidentiables are given below:
Presidentiable
Peak Area
Hellengirl
0.0105
Babymosya :(
0.0120
Pacute To
0.0115
Lacanak
0.0098
Isgwapako
0.0058
Abinyaforever
0.0190
Transcribed Image Text:A. Calculate the regression equation and the R-squared value.
TLA: Chromatography
B. Calculate the concentration of cocaine found in the blood samples of the presidentiables.
Which presidential candidate "reliably" tested positive for cocaine?
2. Internal standard method. Apart from cocaine, the analysts took the liberty to test for other
drugs. Due to lack of standards, the analysts only used the "spiking" method or the internal
standard method. The following are the results of the spiking method.
A. Test for party drug X (Spiked with 1.000 ppm standard solution of party drug X)
Presidentiable
Unspiked sample (Peak
Area)
Spiked sample (Peak Area)
Hellengirl
0.0150
0.1055
Babymosya :(
0.0260
0.0750
PacuteTo
0.0098
0.2048
Lacanak
0.0250
0.0854
Isgwapaako
0.0450
0.0987
Abinyaforever
0.0050
0.0956
Calculate the concentration of party drug X in the blood samples of the presidential candidates.
Suppose the LOD for party drug X is 0.200 ppm, which of the presidential candidates "reliably"
tested for party drug X?
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