26. Cyclophosphamide is a prodrug converted to nitrogen mustard as shown in the following scheme. Cyclophosphamide is thus classified as HÖ) CI P450 CI H2N Cyclophosphamide B: H2N H. HPO, + NH3 + spontaneous OR phosphoramidase HN A. Bipartate prodrug B. Tripartite prodrug C. Bioprecursor prodrug D. Mutual prodrug

Introduction to General, Organic and Biochemistry
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ISBN:9781285869759
Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Publisher:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Chapter20: Carbohydrates
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26. Cyclophosphamide is a prodrug converted to nitrogen mustard as shown in the following
scheme. Cyclophosphamide is thus classified as
HÖ)
CI
P450
H2N
P-N
Cyclophosphamide
B:
H2N
H.
HPO, + NH3 +
HN
spontaneous OR
phosphoramidase
A. Bipartate prodrug
B. Tripartite prodrug
C. Bioprecursor prodrug
D. Mutual prodrug
Transcribed Image Text:26. Cyclophosphamide is a prodrug converted to nitrogen mustard as shown in the following scheme. Cyclophosphamide is thus classified as HÖ) CI P450 H2N P-N Cyclophosphamide B: H2N H. HPO, + NH3 + HN spontaneous OR phosphoramidase A. Bipartate prodrug B. Tripartite prodrug C. Bioprecursor prodrug D. Mutual prodrug
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