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21. GABA, benzodiazepines and barbituates share a common receptor target and elicit similar pharmacodynamic responses yet are susceptible to different antagonists. Which property or process best explains this observation? a) The three molecules target different sub-types of the receptor b) The three molecules are different types of ligands (e.g. full, partial, inverse agonists) c) The three molecules have affinity for distinct binding sites on the receptor d) The three molecules activate different G-proteins e) The three molecules interact with different repressor proteins

21. GABA, benzodiazepines and barbituates share a common receptor target and elicit similar pharmacodynamic responses yet are susceptible to different antagonists. Which property or process best explains this observation? a) The three molecules target different sub-types of the receptor b) The three molecules are different types of ligands (e.g. full, partial, inverse agonists) c) The three molecules have affinity for distinct binding sites on the receptor d) The three molecules activate different G-proteins e) The three molecules interact with different repressor proteins

Essentials of Pharmacology for Health Professions
Essentials of Pharmacology for Health Professions
7th Edition
ISBN:9781305441620
Author:WOODROW
Publisher:WOODROW
Chapter16: Gastrointestinal Drugs
Section: Chapter Questions
Problem 16CRQ
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21. GABA, benzodiazepines and barbituates share a common receptor target and elicit similar pharmacodynamic responses yet are susceptible to different antagonists. Which property or process best explains this observation? a) The three molecules target different sub-types of the receptor b) The three molecules are different types of ligands (e.g. full, partial, inverse agonists) c) The three molecules have affinity for distinct binding sites on the receptor d) The three molecules activate different G-proteins e) The three molecules interact with different repressor proteins
Transcribed Image Text:21. GABA, benzodiazepines and barbituates share a common receptor target and elicit similar pharmacodynamic responses yet are susceptible to different antagonists. Which property or process best explains this observation? a) The three molecules target different sub-types of the receptor b) The three molecules are different types of ligands (e.g. full, partial, inverse agonists) c) The three molecules have affinity for distinct binding sites on the receptor d) The three molecules activate different G-proteins e) The three molecules interact with different repressor proteins
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