20 Carbamazepine tablets were found to weigh 10.000 g in total. The tablets were ground to a fine powder using a pestle and mortar. A 313.2 mg sample of the powder was boiled with 25ml ethanol for a few minutes. The hot mixture was stirred in a closed flask for 10 minutes and filtered through sintered glass. The flask and filter were washed with ethanol and the washings combined with the filtrate. The cooled mixture was made up to 100ml with ethanol (soln A). 5ml of the ethanol extract was diluted to 250ml with ethanol (soln B) and the absorbance of the resulting solution was found to be 0.598 absorbance units at a wavelength of 285nm. The A1%,1cm was 490? a) Calculate the total amount (in mg) of carbamazepine in solution B (1 decimal) Answer = mg b) Calculate the total amount (in mg) of carbamazepine in solution A (1 decimal) Answer = mg C) Calculate the amount (in mg) of carbamazepine in a single tablet. (1 decimal) Answer =

20 Carbamazepine tablets were found to weigh 10.000 g in total. The tablets were ground to a fine powder using a pestle and mortar. A 313.2 mg sample of the powder was boiled with 25ml ethanol for a few minutes. The hot mixture was stirred in a closed flask for 10 minutes and filtered through sintered glass. The flask and filter were washed with ethanol and the washings combined with the filtrate. The cooled mixture was made up to 100ml with ethanol (soln A). 5ml of the ethanol extract was diluted to 250ml with ethanol (soln B) and the absorbance of the resulting solution was found to be 0.598 absorbance units at a wavelength of 285nm. The A1%,1cm was 490? a) Calculate the total amount (in mg) of carbamazepine in solution B (1 decimal) Answer = mg b) Calculate the total amount (in mg) of carbamazepine in solution A (1 decimal) Answer = mg C) Calculate the amount (in mg) of carbamazepine in a single tablet. (1 decimal) Answer =

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

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