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- 3) Propose a mechanism for the following reaction. HO H2SO4Draw the structure of the hydroxyaldehyde product from the self-aldol reaction of each of the following aldehydes: (a) propanal; (b) phenylethanal; (c) 3-phenylpropanal; (d) benzaldehyde.Provide a retrosynthesis and a synthesis for each of the following compounds starting from the designated starting materials and any other necessary reagents.
- What reagents are required to carry out the following synthesis?4. Tertiary amines undergo reversible conjugate additions to a,ß-unsaturated carbonyls. The reaction shown below uses this phenomenon followed by an aldol-like process to obtain the given product. Show a detailed mechanism for this reaction. The structure of one of the intermediates is shown below to assist in drawing the mechanism ОН О Ph + Ph H. H2O/E1OH ОН О intermediate: Phi `NMe3Propose a synthesis for the following reaction
- What is the product of the following sequence of reactions? D | NaOH NaNH2 H3O+ || ||| explain each steps..explanation needed. don't give Handwritten answer IV NH₂When treated with base, the following compound undergoes an intramolecular aldol reaction and dehydration to give a product containing a ring. H Propose a structure for this product. base C4H6O + HODraw the structures of the initially formed enol tautomers in the reactions of propyne and dicyclohexylethyne with dicyclohexylborane followed by NaOHNaOH and H2O2H2O2
- 2 H3C H3C H C→XT OH H3C The aldol reaction is a carbonyl condensation reaction between two carbonyl partners and involves a combination of nucleophilic addition and a-substitution steps. One partner is converted into an enolate ion nucleophile and adds to the electrophilic carbonyl group of the second partner. In the classic aldol reaction, the carbonyl partners are aldehydes or ketones, although aldehydes are more reactive. The product is a ß-hydroxy carbonyl compound. base :0: OH H H Under reaction conditions slightly more vigorous than those employed for the aldol reaction, the ß-hydroxyl group is eliminated in an E1cB dehydration to give an a,ß-unsaturated carbonyl compound. Draw curved arrows to show the movement of electrons in this step of the mechanism. Arrow-pushing Instruct ns H3C heat OH H3C :0: H + H₂O HDraw the structures A, B and C for the reaction sequence below.Draw reaction mechanisms with all reactants, arrows, intermediates, and products. Your mechanism must account for all the products if more than one product is formed. 4-methycyclohexanol with phosphoric acid H3PO4 to for 1-methycyclohexene, 3- methylcyclohexene and 4-methycyclohexene