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2. Describe or draw the most suitable immunological assays or experiments for the following hypothetical situations. Aside from Smabl and Smab2, available are various secondary antibodies. You can create your own reagents, if necessary. 2A. Tonga, a South Pacific island, was one of the few exceptions in the world that were spared from Covid outbreaks until a massive volcano eruption on Jan 15, 2022. Following the arrival of international assistance, more and more peoples are showing Covid symptoms, while majority of Tonga citizens have not yet received Covid vaccines. Tonga government wishes to determine the percentage of its citizens have been infected and who were infected in the first wave and who were infected later. Design an assay for Tonga and explain the results. 2B. Design a sensitive test to identify the citizens who are currently infected with Covid viruses from the nose swap. 2C. You wish to test that patients succumbed to Covid pneumonia (lung inflammation) is due to excessive numbers of antigen presenting cells (APC) recruited to the lymph nodes in the chest cavity and activate nearby T cells, which in turn produce massive amounts of IL-6, a pro- inflammatory cytokine. A nearby hospital can supply chest lymph nodes from patients that died from Covid and from healthy people. Describe your experiments and predict the results if your hypothesis is correct.

2. Describe or draw the most suitable immunological assays or experiments for the following hypothetical situations. Aside from Smabl and Smab2, available are various secondary antibodies. You can create your own reagents, if necessary. 2A. Tonga, a South Pacific island, was one of the few exceptions in the world that were spared from Covid outbreaks until a massive volcano eruption on Jan 15, 2022. Following the arrival of international assistance, more and more peoples are showing Covid symptoms, while majority of Tonga citizens have not yet received Covid vaccines. Tonga government wishes to determine the percentage of its citizens have been infected and who were infected in the first wave and who were infected later. Design an assay for Tonga and explain the results. 2B. Design a sensitive test to identify the citizens who are currently infected with Covid viruses from the nose swap. 2C. You wish to test that patients succumbed to Covid pneumonia (lung inflammation) is due to excessive numbers of antigen presenting cells (APC) recruited to the lymph nodes in the chest cavity and activate nearby T cells, which in turn produce massive amounts of IL-6, a pro- inflammatory cytokine. A nearby hospital can supply chest lymph nodes from patients that died from Covid and from healthy people. Describe your experiments and predict the results if your hypothesis is correct.

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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2. Describe or draw the most suitable immunological assays or experiments for the following hypothetical situations. Aside from Smab1 and Smab2, available are various secondary antibodies. You can create your own reagents, if necessary. 2A. Tonga, a South Pacific island, was one of the few exceptions in the world that were spared from Covid outbreaks until a massive volcano eruption on Jan 15, 2022. Following the arrival of international assistance, more and more peoples are showing Covid symptoms, while majority of Tonga citizens have not yet received Covid vaccines. Tonga government wishes to determine the percentage of its citizens have been infected and who were infected in the first wave and who were infected later. Design an assay for Tonga and explain the results. 2B. Design a sensitive test to identify the citizens who are currently infected with Covid viruses from the nose swap. 2C. You wish to test that patients succumbed to Covid pneumonia (lung inflammation) is due to excessive numbers of antigen presenting cells (APC) recruited to the lymph nodes in the chest cavity and activate nearby T cells, which in turn produce massive amounts of IL-6, a pro- inflammatory cytokine. A nearby hospital can supply chest lymph nodes from patients that died from Covid and from healthy people. Describe your experiments and predict the results if your hypothesis is correct.
Transcribed Image Text:2. Describe or draw the most suitable immunological assays or experiments for the following hypothetical situations. Aside from Smab1 and Smab2, available are various secondary antibodies. You can create your own reagents, if necessary. 2A. Tonga, a South Pacific island, was one of the few exceptions in the world that were spared from Covid outbreaks until a massive volcano eruption on Jan 15, 2022. Following the arrival of international assistance, more and more peoples are showing Covid symptoms, while majority of Tonga citizens have not yet received Covid vaccines. Tonga government wishes to determine the percentage of its citizens have been infected and who were infected in the first wave and who were infected later. Design an assay for Tonga and explain the results. 2B. Design a sensitive test to identify the citizens who are currently infected with Covid viruses from the nose swap. 2C. You wish to test that patients succumbed to Covid pneumonia (lung inflammation) is due to excessive numbers of antigen presenting cells (APC) recruited to the lymph nodes in the chest cavity and activate nearby T cells, which in turn produce massive amounts of IL-6, a pro- inflammatory cytokine. A nearby hospital can supply chest lymph nodes from patients that died from Covid and from healthy people. Describe your experiments and predict the results if your hypothesis is correct.
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