2. Choose the correct statements about the eye development A. Hh, which is expressed by the developing photoreceptors in the posterior eye disc, induces cells in the morphogenetic furrow (MF) to express DPP, which is the ligand of DPP (BMP) signaling. B. Wg and Notch signaling inhibit while Hh and DPP promote the co-expression of RD genes including Ey. (Eyeless) and Eya (Eyes absent) in the preproneural (PPN) domain anterior to the MF. C. Eya, sine oculis (so), and Eyg (Eyegone) are the retinal determination (RD) network genes required for retinal determination and induction of atonal expression. D. EGFR signaling is required for the differentiation of all the photoreceptor neurons after R8 determination. In addition EGFR signaling is also required for maintaining cell survival in posterior eye discs. E. During Drosophila eye development, cell proliferation in the second mitotic wave is required to provide sufficient undifferentiated cells surrounding the differentiating photoreceptors for the stepwise recruitment of additional cell types into the developing ommatidia. F. Eyeless and Eyegone have similar structure and function as the mammalian Pax6 protein. Loss of function mutations of either ey or eyg cause loss of eye tissues and ectopic expression of either gene in wing discs will induce ectopic eye formation.
2. Choose the correct statements about the eye development A. Hh, which is expressed by the developing photoreceptors in the posterior eye disc, induces cells in the morphogenetic furrow (MF) to express DPP, which is the ligand of DPP (BMP) signaling. B. Wg and Notch signaling inhibit while Hh and DPP promote the co-expression of RD genes including Ey. (Eyeless) and Eya (Eyes absent) in the preproneural (PPN) domain anterior to the MF. C. Eya, sine oculis (so), and Eyg (Eyegone) are the retinal determination (RD) network genes required for retinal determination and induction of atonal expression. D. EGFR signaling is required for the differentiation of all the photoreceptor neurons after R8 determination. In addition EGFR signaling is also required for maintaining cell survival in posterior eye discs. E. During Drosophila eye development, cell proliferation in the second mitotic wave is required to provide sufficient undifferentiated cells surrounding the differentiating photoreceptors for the stepwise recruitment of additional cell types into the developing ommatidia. F. Eyeless and Eyegone have similar structure and function as the mammalian Pax6 protein. Loss of function mutations of either ey or eyg cause loss of eye tissues and ectopic expression of either gene in wing discs will induce ectopic eye formation.
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
Related questions
Question
Transcribed Image Text:2. Choose the correct statements about the eye development
A. Hh, which is expressed by the developing photoreceptors in the posterior eye disc, induces cells in the
morphogenetic furrow (MF) to express DPP, which is the ligand of DPP (BMP) signaling.
B. Wg and Notch signaling inhibit while Hh and DPP promote the co-expression of RD genes including Ey
(Eyeless) and Eya (Eyes absent) in the preproneural (PPN) domain anterior to the MF.
C. Eya, sine oculis (so), and Eyg (Eyegone) are the retinal determination (RD) network genes required for
retinal determination and induction of atonal expression.
D. EGFR signaling is required for the differentiation of all the photoreceptor neurons after R8
determination. In addition EGFR signaling is also required for maintaining cell survival in posterior eye
discs.
E. During Drosophila eye development, cell proliferation in the second mitotic wave is required to provide
sufficient undifferentiated cells surrounding the differentiating photoreceptors for the stepwise
recruitment of additional cell types into the developing ommatidia.
F. Eyeless and Eyegone have similar structure and function as the mammalian Pax6 protein. Loss of
function mutations of either ey or eyg cause loss of eye tissues and ectopic expression of either gene in
wing discs will induce ectopic eye formation.
Expert Solution
This question has been solved!
Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.
This is a popular solution!
Trending now
This is a popular solution!
Step by step
Solved in 2 steps
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Recommended textbooks for you
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:
9780134580999
Author:
Elaine N. Marieb, Katja N. Hoehn
Publisher:
PEARSON
Biology 2e
Biology
ISBN:
9781947172517
Author:
Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:
OpenStax
Anatomy & Physiology
Biology
ISBN:
9781259398629
Author:
McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:
Mcgraw Hill Education,
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:
9780134580999
Author:
Elaine N. Marieb, Katja N. Hoehn
Publisher:
PEARSON
Biology 2e
Biology
ISBN:
9781947172517
Author:
Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:
OpenStax
Anatomy & Physiology
Biology
ISBN:
9781259398629
Author:
McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:
Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:
9780815344322
Author:
Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:
W. W. Norton & Company
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:
9781260159363
Author:
Martin, Terry R., Prentice-craver, Cynthia
Publisher:
McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)
Biology
ISBN:
9781260231700
Author:
Sylvia S. Mader, Michael Windelspecht
Publisher:
McGraw Hill Education