Homework Help is Here – Start Your Trial Now!
Science
Biochemistry
2. a) Energetics of the electron transport. In the oxidative phase of oxidative phosphorylation, electrons are passed from NADH and ultimately to molecular oxygen through an electron transport chain comprised of multiple redox centers. Assume that an electron is passed through the chain along the route shown below. Clearly, there are steps missing, but we will skip those to emphasize the energetics of the electron transport. Calculate DE' and DGº' for each electron transfer step and record the values in the table. The reduction potentials for each of the redox centers are given in table 11.1. (F=96.4 kJ/V mol) Route: NADH → (Fe-S)N-5,6 Coenzyme Q → Cytochrome c₁ → Cytochrome a3 → 0₂ Table 11.1 STANDARD REDUCTION POTENTIALS (E°) FOR SELECTED ELECTRON CARRIERS IN THE ELECTRON TRANSPORT SYSTEM Electron carriers NAD +H + 2e → NADH Complex I (NADH-ubiquinone oxidoreductase) Fe-S (N-1b) Fe-S (N-3,4) Fe-S (N-5,6) Complex II (succinate dehydrogenase) FAD+ 2H +2e → FADH₂ (enzyme bound) Fe-S (S-1) Cytochrome b560 Coenzyme Q + 2 H + 2e Complex IIll (ubiquinone-cytochrome c oxidoreductase) Cytochrome by Cytochrome b Fe-S Cytochrome c₁ Cytochrome c (Cyt c) Complex IV (cytochrome coxidase) Cytochrome a CUA Cytochrome az O₂ +2H + 2e →H₂O E" (V) -0.32 -0.25 -0.24 -0.27 -0.04 -0.03 -0.08 +0.04 +0.03 -0.03 +0.28 +0.21 +0.23 +0.21 +0.24 +0.38 +0.82 Direction of flow e transferred from to NADH (Fe-S)N-5,6 (Fe-S)N-5,6 Coenzyme Q Coenzyme Q → Cytochrome c₁ Cytochrome c₁ → Cytochrome a3 Cytochrome a3→ O₂ AE⁰¹ -nFAE⁰¹= AG⁰¹

2. a) Energetics of the electron transport. In the oxidative phase of oxidative phosphorylation, electrons are passed from NADH and ultimately to molecular oxygen through an electron transport chain comprised of multiple redox centers. Assume that an electron is passed through the chain along the route shown below. Clearly, there are steps missing, but we will skip those to emphasize the energetics of the electron transport. Calculate DE' and DGº' for each electron transfer step and record the values in the table. The reduction potentials for each of the redox centers are given in table 11.1. (F=96.4 kJ/V mol) Route: NADH → (Fe-S)N-5,6 Coenzyme Q → Cytochrome c₁ → Cytochrome a3 → 0₂ Table 11.1 STANDARD REDUCTION POTENTIALS (E°) FOR SELECTED ELECTRON CARRIERS IN THE ELECTRON TRANSPORT SYSTEM Electron carriers NAD +H + 2e → NADH Complex I (NADH-ubiquinone oxidoreductase) Fe-S (N-1b) Fe-S (N-3,4) Fe-S (N-5,6) Complex II (succinate dehydrogenase) FAD+ 2H +2e → FADH₂ (enzyme bound) Fe-S (S-1) Cytochrome b560 Coenzyme Q + 2 H + 2e Complex IIll (ubiquinone-cytochrome c oxidoreductase) Cytochrome by Cytochrome b Fe-S Cytochrome c₁ Cytochrome c (Cyt c) Complex IV (cytochrome coxidase) Cytochrome a CUA Cytochrome az O₂ +2H + 2e →H₂O E" (V) -0.32 -0.25 -0.24 -0.27 -0.04 -0.03 -0.08 +0.04 +0.03 -0.03 +0.28 +0.21 +0.23 +0.21 +0.24 +0.38 +0.82 Direction of flow e transferred from to NADH (Fe-S)N-5,6 (Fe-S)N-5,6 Coenzyme Q Coenzyme Q → Cytochrome c₁ Cytochrome c₁ → Cytochrome a3 Cytochrome a3→ O₂ AE⁰¹ -nFAE⁰¹= AG⁰¹

Biochemistry
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
See similar textbooks
icon
Related questions
Question
2. a) Energetics of the electron transport. In the oxidative phase of oxidative phosphorylation, electrons are passed from NADH and ultimately to molecular oxygen through an electron transport chain comprised of multiple redox centers. Assume that an electron is passed through the chain along the route shown below. Clearly, there are steps missing, but we will skip those to emphasize the energetics of the electron transport. Calculate DE' and DGº' for each electron transfer step and record the values in the table. The reduction potentials for each of the redox centers are given in table 11.1. (F=96.4 kJ/V mol) Route: NADH → (Fe-S)N-5,6 Coenzyme Q → Cytochrome c₁ → Cytochrome a3 ⇒ 0₂ Table 11.1 STANDARD REDUCTION POTENTIALS (E°') FOR SELECTED ELECTRON CARRIERS IN THE ELECTRON TRANSPORT SYSTEM Electron carriers NAD+ + H+ + 2e → NADH Complex I (NADH-ubiquinone oxidoreductase) Fe-S (N-1b) Fe-S (N-3,4) Fe-S (N-5,6) Complex II (succinate dehydrogenase) FAD + 2H+ + 2e → FADH₂ (enzyme bound) Fe-S (S-1) Cytochrome b560 Coenzyme Q + 2H+ + 2 e Complex III (ubiquinone-cytochrome c oxidoreductase) Cytochrome b Cytochrome b Fe-S Cytochrome c₁ Cytochrome c (Cyt c) Complex IV (cytochrome c oxidase) Cytochrome a Cu Cytochrome az O₂ + 2H+ + 2e → H₂O E° (V) -0.32 -0.25 -0.24 -0.27 -0.04 -0.03 -0.08 +0.04 +0.03 -0.03 +0.28 +0.21 +0.23 +0.21 +0.24 +0.38 +0.82 Direction of e flow e transferred from to NADH → (Fe-S)N-5,6 (Fe-S)N-5,6 → Coenzyme Q Coenzyme Q → Cytochrome c₁ Cytochrome c₁ → Cytochrome a3 Cytochrome a3⇒ 0₂ AE⁰¹ -nFAE⁰¹= AG⁰¹
Transcribed Image Text:2. a) Energetics of the electron transport. In the oxidative phase of oxidative phosphorylation, electrons are passed from NADH and ultimately to molecular oxygen through an electron transport chain comprised of multiple redox centers. Assume that an electron is passed through the chain along the route shown below. Clearly, there are steps missing, but we will skip those to emphasize the energetics of the electron transport. Calculate DE' and DGº' for each electron transfer step and record the values in the table. The reduction potentials for each of the redox centers are given in table 11.1. (F=96.4 kJ/V mol) Route: NADH → (Fe-S)N-5,6 Coenzyme Q → Cytochrome c₁ → Cytochrome a3 ⇒ 0₂ Table 11.1 STANDARD REDUCTION POTENTIALS (E°') FOR SELECTED ELECTRON CARRIERS IN THE ELECTRON TRANSPORT SYSTEM Electron carriers NAD+ + H+ + 2e → NADH Complex I (NADH-ubiquinone oxidoreductase) Fe-S (N-1b) Fe-S (N-3,4) Fe-S (N-5,6) Complex II (succinate dehydrogenase) FAD + 2H+ + 2e → FADH₂ (enzyme bound) Fe-S (S-1) Cytochrome b560 Coenzyme Q + 2H+ + 2 e Complex III (ubiquinone-cytochrome c oxidoreductase) Cytochrome b Cytochrome b Fe-S Cytochrome c₁ Cytochrome c (Cyt c) Complex IV (cytochrome c oxidase) Cytochrome a Cu Cytochrome az O₂ + 2H+ + 2e → H₂O E° (V) -0.32 -0.25 -0.24 -0.27 -0.04 -0.03 -0.08 +0.04 +0.03 -0.03 +0.28 +0.21 +0.23 +0.21 +0.24 +0.38 +0.82 Direction of e flow e transferred from to NADH → (Fe-S)N-5,6 (Fe-S)N-5,6 → Coenzyme Q Coenzyme Q → Cytochrome c₁ Cytochrome c₁ → Cytochrome a3 Cytochrome a3⇒ 0₂ AE⁰¹ -nFAE⁰¹= AG⁰¹
Expert Solution
steps

Step by step

Solved in 3 steps with 26 images

SEE SOLUTIONCheck out a sample Q&A here
Blurred answer
Similar questions
  • SEE MORE QUESTIONS
Recommended textbooks for you
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781319114671
Author:
Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:
W. H. Freeman
Lehninger Principles of Biochemistry
Lehninger Principles of Biochemistry
Biochemistry
ISBN:
9781464126116
Author:
David L. Nelson, Michael M. Cox
Publisher:
W. H. Freeman
Fundamentals of Biochemistry: Life at the Molecul…
Fundamentals of Biochemistry: Life at the Molecul…
Biochemistry
ISBN:
9781118918401
Author:
Donald Voet, Judith G. Voet, Charlotte W. Pratt
Publisher:
WILEY
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781305961135
Author:
Mary K. Campbell, Shawn O. Farrell, Owen M. McDougal
Publisher:
Cengage Learning
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781305577206
Author:
Reginald H. Garrett, Charles M. Grisham
Publisher:
Cengage Learning
Fundamentals of General, Organic, and Biological …
Fundamentals of General, Organic, and Biological …
Biochemistry
ISBN:
9780134015187
Author:
John E. McMurry, David S. Ballantine, Carl A. Hoeger, Virginia E. Peterson
Publisher:
PEARSON
SEE MORE TEXTBOOKS