12. The method of administering a drug can have a stronginfluence on the drug concentration curve. Figure 4.97shows drug concentration curves for penicillin followingvarious routes of administration. Three milligrams perkilogram of body weight were dissolved in water andadministered intravenously (IV), intramuscularly (IM),subcutaneously (SC), and orally (PO). The same quan-tity of penicillin dissolved in oil was administered in-tramuscularly (P-IM). The minimum effective concentra-tion (MEC) is labeled on the graph."25(a) Which method reaches peak concentration thefastest? The slowest?(b) Which method has the largest peak concentration?The smallest?(c) Which method wears off the fastest? The slowest?(d) Which method has the longest effective duration?The shortest?(e) When penicillin is administered orally, for approxi-mately what time interval is it effective?concentration of penicilinserum (igimi)100.5IV0.10.050.01MECt (hours)2418Figure 4.97

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Answered: 12. The method of administering a drug…

Calculus: Early Transcendentals

8th Edition

ISBN:9781285741550

Author:James Stewart

Publisher:James Stewart

Chapter1: Functions And Models

Section: Chapter Questions

Problem 1RCC: (a) What is a function? What are its domain and range? (b) What is the graph of a function? (c) How...

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In North America, between 100 million and 1 billion birds die each year by crashing into windows on buildings, more than any other human-related cause. This figure represents up to 5% of all birds in the area. One possible solution is to construct windows angled downward slightly, so that they reflect the ground rather than an image of the sky to a flying bird. An experiment by Klem et al. (2004) compared the number of birds that died as a result of vertical windows, windows angled 20 degrees off vertical, and windows angled 40 degrees off vertical. The angles were randomly assigned with equal probability to six windows and changed daily; assume for this exercise that windows and window locations were identical in every respect except angle. Over the course of the experiment, 30 birds were killed by windows in the vertical orientation, 15 were killed by windows set at 20 degrees off vertical, and 8 were killed by windows set at 40 degrees off vertical. . Clearly state an appropriate…
A paper gives data on x = change in Body Mass Index (BMI, in kilograms/meter2) and y = change in a measure of depression for patients suffering from depression who participated in a pulmonary rehabilitation program. The table below contains a subset of the data given in the paper and are approximate values read from a scatterplot in the paper. BMI Change (kg/m²) Depression Score Change S = The accompanying computer output is from Minitab. Depression score change 15- 10- -0.5 S Fitted Line Plot Depression score change = 6.577 +5.440 BMI change 20- 5.30586 Coefficients T 0.0 0.5 -0.5 R-sq 25.96% - 1 Term Coef Constant 6.577 BMI change 5.440 % 0.5 BMI change 1.0 SE Coef 2.28 2.90 9 0 0.1 0.7 0.8 1 1.5 4 T-Value 2.88 1.87 Interpret this estimate. s is the typical amount by which the ---Select--- line. 4 5 Regression Equation Depression score change = 6.577 +5.440 BMI change P-Value 0.0164 0.0906 S 5.30586 25.96% R-Sq R-Sq (adj) 18.56% 8 (b) Give a point estimate of o. (Round your answer to…
Can someone calculate this problem and explain it to me?
Evaluate the following grades: (Case 1) a grade of 220 points on an exam with u = 200 ando = 21. (Case 2) a grade of 90 points on an exam with µ = 80 and o = 8. * The better grade cannot be determined. The first grade is better. The two grades are equal statistically. The second grade is better.
Wrinkle recovery angle and tensile strength are the two most important characteristics for evaluating the performance of crosslinked cotton fabric. An increase in the degree of crosslinking, as determined by ester carboxyl band absorbance, improves the wrinkle resistance of the fabric (at the expense of reducing mechanical strength). The accompanying data on x = absorbance and y = wrinkle resistance angle was read from a graph in the paper "Predicting the Performance of Durable Press Finished Cotton Fabric with Infrared Spectroscopy".† x 0.115 0.126 0.183 0.246 0.282 0.344 0.355 0.452 0.491 0.554 0.651 y 334 342 355 363 365 372 381 392 400 412 420 Here is regression output from Minitab: Predictor Constant absorb S = 3.60498 Coef 321.878 156.711 SOURCE Regression Residual Error Total SE Coef 2.483 6.464 R-Sq = 98.5% DF 1 9 10 SS 7639.0 117.0 7756.0 T 129.64 24.24 0.000 0.000 R-Sq (adj) = 98.3% MS 7639.0 13.0 F P 587.81 (a) Does the simple linear regression model appear to be…
The US Department of Agriculture collected nutrient data on various types of cheeses. Two nutrients of concern to people trying to eat healthier are saturated fat and sodium. The given JMP applet shows scatterplots of the amount of sodium in milligrams by the amount of saturated fat in grams for these cheeses.t O JMP Applet jmp ? Sodium (mg) By Saturated Fat (g) Sodium (mg) By Saturated Fat (15 g - 21 g) 2000 2000 1500- 1500 1000- 1000- 500- 500- 0- 0- 20 15 16 20 21 Saturated Fat (g) Saturated Fat (g) Sodium (1,000 mg - 2,000 mg) By Saturated Fat (g) 1800- 1000- 1400- 1200- 1000- 10 15 20 Saturated Fat (g) II (Bu) unipos III (Bu) unipos (Bu) unipos
Water is poured into a large, cone-shaped cistern. The volume of water, measured in cm, is reported at Which of the following would linearize the data for volume and time? different time intervals, measured in seconds. The scatterplot of volume versus time showed a curved Seconds, cm3 O In(Seconds), cm3 Seconds, In(cm') pattern. O In(Seconds), In(cm³)
Fill the chi square for Cross 1 and Cross 2 from the following data in the attached image: Cross 1: Phenotypes Ratio Observed Expected (O-E)2/E Totals X2 = Cross 2: Phenotypes Ratio Observed Expected (O-E)2/E Totals X2 =
In North America, between 100 million and 1 billion birds die each year by crashing into windows on buildings, more than any other human-related cause. This figure represents up to 5% of all birds in the area. One possible solution is to construct windows angled downward slightly so that they reflect the ground rather than an image of the sky to a flying bird. An experiment by Klem et al. (2004) compared the number of birds that died as a result of vertical windows, windows angled 20 degrees off vertical, and windows angled 40 degrees off vertical. The angles were randomly assigned with equal probability to six windows and changed daily; assume for this exercise that windows and window locations were identical in every respect except angle. Over the course of the experiment, 30 birds were killed by windows in the vertical orientation, 15 were killed by windows set at 20 degrees off vertical, and 8 were killed by windows set at 40 degrees off vertical. a. Clearly state an appropriate…
Lecture(8.8): The amount of time people engage in physical activity mat be related to health outcome. Those who report that they spend more than 15 hours are put into one while those who spend less 10 were put into another group. (Those who fall in between 10 and 15 were left out of the study); The reaearcher then ask the participants to wear a monitor for one month. The average time in minutes is recorded and shown below . Is there any evidence that on average people who watch less than 10 hours watching televsion spend more time on physical activity.?. Test the hypotheses at (alpha=0.05) using the 5 step procedure <10 hours 75 63 118 35 82 >15 hours 62 6 78 43 22 33
Suppose μ₁ and ₂ are true mean stopping distances at 50 mph for cars of a certain type equipped with two different types of braking systems. The data follows: m = 8, x = 115.6, $₁=5.09, n = 8, y = 129.5, and s₂ = 5.33. Calculate a 95% CI for the difference between true average stopping distances for cars equipped with system 1 and cars equipped with system 2. (Round your answers to two decimal places.) USE SALT Does the interval suggest that precise information about the value of this difference is available? O Because the interval is so narrow, it appears that precise information is available. O Because the interval is so wide, it appears that precise information is available. O Because the interval is so narrow, it appears that precise information is not available. O Because the interval is so wide, it appears that precise information is not available.
The following data refers to yield of tomatoes (kg/plot) for four different levels of salinity. Salinity level here refers to electrical conductivity (EC), where the chosen levels were EC = 1.6, 3.8, 6.0, and 10.2 nmhos/cm. (Use i = 1, 2, 3, and 4 respectively.) 1.6: 59.4 53.4 56.3 63.2 58.4 3.8: 55.9 59.7 52.7 54.2 6.0: 51.7 48.2 53.9 49.0 10.2: 44.3 48.3 40.7 47.2 46.7 W23 = W 24 = W34 = USE SALT Apply the modified Tukey's method to identify significant differences among us. (Round your answers to two decimal places.) W12 = W13 = W14= Which pairs are significantly different? (Select all that apply.) Othe group and the 3.8 group the 1.6 group and the 6.0 group the 1.6 group and the 10.2 group the 3.8 group and the 6.0 group the 3.8 group and the 10.2 group O the 6.0 group and the 10.2 group There are no significant differences.

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