10. Two men with hyperglycemia visited an endocrinologist. One patient wasdiagnoscd with Itsenko-Cushing's discase; another was diagnosed with diabetesmellitus. Explain the differentiation in these disorders. What metabolic changeswill be characteristic in these patients? For answer:a) compare the changes in carbohydrate metabolism for both patients;b) cnumcrate the metabolic changes for diabetes mellitus;c) explain which disorder causes ketoacidosis and why.LA pationtoomplainteoforedroueinoce

Cushing syndrome occurs due to an exposure to high corticosteroid levels for a long period of time…

Answered: 10. Two men with hyperglycemia visited…

Phlebotomy Essentials

6th Edition

ISBN:9781451194524

Author:Ruth McCall, Cathee M. Tankersley MT(ASCP)

Publisher:Ruth McCall, Cathee M. Tankersley MT(ASCP)

Chapter1: Phlebotomy: Past And Present And The Healthcare Setting

Section: Chapter Questions

Problem 1SRQ

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Patient who had undergone a complex maxillofacial operation could not takefood during 2 days, but glucose level in the patient's blood during that period wason the lower limit of normal. What mechanisms facilitate the maintenance ofnormal level of glucose in prolonged starvation? To answer this question:a) indicate normal fasting blood glucose level;b) draw the metabolic pathway ensuring glucose synthesis in patient's body duringa period of starvation, mark the enzymes and coenzymes;c) list the substrates of this process and its localization.
Which compounds would accumulate in an individual with beriberi (caused by thiamine deficiency)?
explain why natural protease inhibitors (peptide extracts from the pancreas of cattle - aprotinin) can also arrest the destruction of pancreatic proteins, but often cause an allergic reaction.
A six year old boy dies of heart failure. He had mental retardation, short stature, course facial features, corneal, clouding, a large tongue, short, broad fingers, and skeletal dysplasia. He was normal at birth, progressive mental, and physical deterioration began at age 6 month. Examination at autopsy shows cornary artery thickening, and a tracheal narrowing. The most likely cause of these abnormalities is a deficiency of which of the following enzymes? A) alpha 1 antitrypsin B) galactocerebrosidase C) glycogen phosphorylase D) alpha -L- iduronidase E) type IV Collagenase
8. Ketone bodies were found in the urine of the patient with diabetes mellitus. Explain the sequence of metabolic changes resulting in ketonuria. For that answer the question and do the following tasks: a) what are the ranges of ketone bodics in blood of the healthy pcople and the patients with diabetes mellitus? b) explain the main changes in hormonal regulation of patient with diabetes mellitus; c) explain why the level of free fatty acids in the blood is clevated; d) name the pathways of lipid metabolism which becomes more active in patients with diabetes mellitus; e) draw the scheme of ketone body synthesis and oxidation.
Why is amyloid toxic to cellsand how does it contribute toneurodegenerative diseases such asAlzheimer’s disease?
54. Explain the functions of pancreatic amylase, aminopeptidase, gastric lipase, and deoxyribonuclease.?
Give details of secondary structure of Mature Bovine insulin
A 9 year old mentally retarded girl with a protuberant abdomen, short stature, coarse facial features and cloudy corneas. skeletal malformations include dysostosis Multiplex and Bullet shaped middle phalanx .what is the enzyme deficient in this patient? A)Iduronate sulfatase B) beta - Galactosidase C)alpha - L- Iduronidase D) beta - Glucuronidase
1. With the prevalence in food of peeled cereals or bread made from high-grade flour, hypovitaminosis B1 may occur. Explain the role that vitamin B, plays in the body. For this: a) name the coenzyme which contains vitamin B, and enzymes, which require this cocnzyme to function; b) write the process in which these enzymes are involved and explain how the process speed will change with a lack of B,; d) what discase develops in the absence of vitamin B,.
(27) An 80-year old man witha 20-year old history of ashthma comes to the physician because of a 24 hour history of a running nose , sore throat , cough,muscle aches, and fatigue. His temperature is 39.5 degrees celcius (103.1F). Zanamivir is prescribed because it inhibits which of the following enzymes? (A) Aldolase (B) Kinase (C) N-acetyl glucosaminidase (D) Neuraminidase (E) Transglycosylase
Explain the mechanism of action for Alteplase as a treatment for Stroke?

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