1.(a) ( ) Trace the course of [1,6-(C-14)-2,5-(C-13)]glucose that is first processed through glycolysis and proceeds into the TCA cycle. For the glycolysis part, use the diagram below to decide where glucose atoms end up in pyruvate. You need to illustrate only the structures of D-glucose, labeling the atoms, and of pyruvate, labeling the origin of the atoms in glucose and the distribution of the carbon isotopes in py- ruvate. After one round of the TCA cycle where will the labeled carbons be found? HO HO- СНЬОН + 2 NAD+ от + 2 NADH + 2 P₁ 2 + 2 ATP HO OH 2 ADP CH3 + 2 H₂O Glucose Pyruvate
1.(a) ( ) Trace the course of [1,6-(C-14)-2,5-(C-13)]glucose that is first processed through glycolysis and proceeds into the TCA cycle. For the glycolysis part, use the diagram below to decide where glucose atoms end up in pyruvate. You need to illustrate only the structures of D-glucose, labeling the atoms, and of pyruvate, labeling the origin of the atoms in glucose and the distribution of the carbon isotopes in py- ruvate. After one round of the TCA cycle where will the labeled carbons be found? HO HO- СНЬОН + 2 NAD+ от + 2 NADH + 2 P₁ 2 + 2 ATP HO OH 2 ADP CH3 + 2 H₂O Glucose Pyruvate
Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter18: Glycolysis
Section: Chapter Questions
Problem 6P: The Reactions and Meehanisms of the Leloir Pathway Write the reactions that permit galactose to be...
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![1.(a) ( ) Trace the course of [1,6-(C-14)-2,5-(C-13)]glucose that is first processed through glycolysis
and proceeds into the TCA cycle. For the glycolysis part, use the diagram below to decide where glucose
atoms end up in pyruvate. You need to illustrate only the structures of D-glucose, labeling the atoms, and
of pyruvate, labeling the origin of the atoms in glucose and the distribution of the carbon isotopes in py-
ruvate. After one round of the TCA cycle where will the labeled carbons be found?
HO
HO-
СНЬОН
+ 2 NAD+
от
+ 2 NADH
+ 2 P₁
2
+ 2 ATP
HO
OH 2 ADP
CH3
+ 2 H₂O
Glucose
Pyruvate](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F7e3218aa-1b65-42a2-9071-7edb43c3a555%2F4d9b97ec-84b6-4fff-90a7-d4a9c1c595bc%2Fxxvvw6j_processed.png&w=3840&q=75)
Transcribed Image Text:1.(a) ( ) Trace the course of [1,6-(C-14)-2,5-(C-13)]glucose that is first processed through glycolysis
and proceeds into the TCA cycle. For the glycolysis part, use the diagram below to decide where glucose
atoms end up in pyruvate. You need to illustrate only the structures of D-glucose, labeling the atoms, and
of pyruvate, labeling the origin of the atoms in glucose and the distribution of the carbon isotopes in py-
ruvate. After one round of the TCA cycle where will the labeled carbons be found?
HO
HO-
СНЬОН
+ 2 NAD+
от
+ 2 NADH
+ 2 P₁
2
+ 2 ATP
HO
OH 2 ADP
CH3
+ 2 H₂O
Glucose
Pyruvate
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