1. why is the ribosome a good drug target? 2. Tetracyclines: a. Where do first generation tetracyclines bind? b. Which step in protein translation do they inhibit? C. Why was it necessary to come out with a third generation tetracycline, and how are they different?

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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5. Macrolides:
a. Which step in protein synthesis does this class of drugs inhibit?
b. Do you think this class of drugs would be more effective in blocking the synthesis
of small or large proteins? Why?
6. Antibiotic resistance is a constant problem. List three ways that bacteria can be resistant
to antibiotics.
Transcribed Image Text:5. Macrolides: a. Which step in protein synthesis does this class of drugs inhibit? b. Do you think this class of drugs would be more effective in blocking the synthesis of small or large proteins? Why? 6. Antibiotic resistance is a constant problem. List three ways that bacteria can be resistant to antibiotics.
1. why is the ribosome a good drug target?
2. Tetracyclines:
a. Where do first generation tetracyclines bind?
b. Which step in protein translation do they inhibit?
C. Why was it necessary to come out with a third generation tetracycline, and how
are they different?
3. What are three ways that 2-deoxystreptamine (2-DOS) aminoglycosides can inhibit
protein synthesis?
4. Chloramphenicol:
a. Where does this drug bind?
b. How does it inhibit protein synthesis?
Transcribed Image Text:1. why is the ribosome a good drug target? 2. Tetracyclines: a. Where do first generation tetracyclines bind? b. Which step in protein translation do they inhibit? C. Why was it necessary to come out with a third generation tetracycline, and how are they different? 3. What are three ways that 2-deoxystreptamine (2-DOS) aminoglycosides can inhibit protein synthesis? 4. Chloramphenicol: a. Where does this drug bind? b. How does it inhibit protein synthesis?
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