1. The RNA nucleotides part of the telomerase structure is used as the for creating the repeated sequence at the end of chromosomes. 2. What end of the DNA is telomerase extending? bra AMO erba 3. What does this extension accomplish? de an 18 of 1 4. Why don't organisms with circular chromosomes also have telomerase?

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Chapter1: The Human Body: An Orientation
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PART 4: TERMINATION OF REPLICATION
When the ends of linear chromosomes are reached there is a 3' overhang of single
stranded DNA. This is because the RNA primer located at this position has been
removed and DNA polymerase cannot
replace that primer with DNA (without a
primer). This apparent dilemma is solved
by an enzyme called Telomerase.
Telomerase extends the DNA at the end
of chromosomes, called telomeres.
Telomeres are stretches of repeated
And yd
5 ITT
3¹
5 TTTTT
3¹ LL
3'
is in
35mming
5'
Telomere Repeats
TITTAGGG TTAGGG TTAGGG 3
5'
CCAAUCCC
of chromosomes.
Telomerase
3
Telomere Repeats
5⁰
VITTAGGGTTAGGG TTAGGG TTAGGG 3
AATCCC AATCCC AAUG( CCAAUCCC 9.0
Telomerase
1. The RNA nucleotides part of the telomerase structure is used as the
In ins
DNA polymerase
DNA sequences. Telomerase recognizes the repeated sequence, binds to it, and then
lays down more nucleotides, lengthening the telomere.
3'
Telomerase is composed of amino acids and RNA nucleotides. In the image above the
amino acids are represented by the half circle shape, and the nucleotides of telomerase
are represented in blue.
2.
What end of the DNA is telomerase extending?
orü ellug brs AMO erb
sh
na AVO erb abriwnu
3. What does this extension accomplish?
for creating the repeated sequence at the end
Hiw
18 of 2
beshemylog el
4. Why don't organisms with circular chromosomes also have telomerase?
Transcribed Image Text:PART 4: TERMINATION OF REPLICATION When the ends of linear chromosomes are reached there is a 3' overhang of single stranded DNA. This is because the RNA primer located at this position has been removed and DNA polymerase cannot replace that primer with DNA (without a primer). This apparent dilemma is solved by an enzyme called Telomerase. Telomerase extends the DNA at the end of chromosomes, called telomeres. Telomeres are stretches of repeated And yd 5 ITT 3¹ 5 TTTTT 3¹ LL 3' is in 35mming 5' Telomere Repeats TITTAGGG TTAGGG TTAGGG 3 5' CCAAUCCC of chromosomes. Telomerase 3 Telomere Repeats 5⁰ VITTAGGGTTAGGG TTAGGG TTAGGG 3 AATCCC AATCCC AAUG( CCAAUCCC 9.0 Telomerase 1. The RNA nucleotides part of the telomerase structure is used as the In ins DNA polymerase DNA sequences. Telomerase recognizes the repeated sequence, binds to it, and then lays down more nucleotides, lengthening the telomere. 3' Telomerase is composed of amino acids and RNA nucleotides. In the image above the amino acids are represented by the half circle shape, and the nucleotides of telomerase are represented in blue. 2. What end of the DNA is telomerase extending? orü ellug brs AMO erb sh na AVO erb abriwnu 3. What does this extension accomplish? for creating the repeated sequence at the end Hiw 18 of 2 beshemylog el 4. Why don't organisms with circular chromosomes also have telomerase?
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