1. The desire steady state concentration of a drug is 5mg/l. Clearance of the drug is 30 1/hr and its volume of distribution is 1501. a) What infusion rate will be necessary to reach the target concentration? b) How long will it take to reach steady state? c) What loading dose will be required to instantaneously achieve the steady state?

1. The desire steady state concentration of a drug is 5mg/l. Clearance of the drug is 30 1/hr and its volume of distribution is 1501. a) What infusion rate will be necessary to reach the target concentration? b) How long will it take to reach steady state? c) What loading dose will be required to instantaneously achieve the steady state?

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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