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- 49. The bioavailability of drug X after oral administration is 38%. Which of the following best explains this level of systemic bioavailability? A) Adipose distribution B) Hepatic metabolism C) Plasma protein binding D) Pulmonary metabolism E) Renal metabolismPlease answer the following questions 1) Vd of a drug will be high when it is distributed in the following tissues except-a) Adipose tissueb) Brain and spinal cordc) Skeletal muscle tissued) Visceral fate) Mesentery tissuef) fats covering kidney and spleen 2) In a 2-comp. open model system the rate of drug disposition between compartents follow-a) zero orderb) 1-orderc) 2-rderd) 3-ordere) mixed orderf) none of the above 3) The likely molecular wt. of a drug for oral absorption is-a) no more than 400b) no more than 350c) no more than 550d) no more than 700e) no more than 650f) no more than 50027. In a life-threatening situation when a therapeutic concentration of a drug is needed immediately, which of the following is the best means for choosing the loading dose? A) Bolus of five times the maintenance dose B) Infusion at five times the normal maintenance rate for 1 half-life C) Maintenance dose times body weight D) Maintenance doses with the dose interval equal to the half-life E) Steady-state plasma concentration times the volume of distribution
- 1 Which of the following is a contraindication to the antiarrhythmic Amiodarone? A) Tachycardia B) Allergy to Lidocaine C) Bradycardia D) Hypertension 2 Which of the following is a common side effect of cholesterol medication? A) Muscle pain B) Diabetes C) Headache D) Decreased urination 3 Which of the following most accurately describes the mechanism of action of a "statin"? A) Inhibits platelet aggregation B) Inhibits sodium excretion in the kidneys C) Inhibits cholesterol production in the liver D) Inhibits sodium reabsorption in the loop of Henle 4 Which of the following is an indication to the antiarrhythmic Amiodarone? A) Bradycardia B) Hypercalcemia C) Hypertension D) Supraventricular Tachycardia (SVT)Which of the following is a contraindication to anticoagulant use? A) Recent injury B) Diabetes C) Asthma D) Dizziness Which of the following is an antiplatelet medication? A) Diltiazem B) Labetalol C) Procainamide D) Aspirin A commonly shared action of all antiarrhythmics is that they _____________________. A) Inhibit calcium absorption B) Cause vasoconstriction C) Slow the heart rate D) Prevent bradycardia Which of the following medications is an ACE inhibitor? A) Aspirin B) Labetalol C) Lisinopril D) Simvastatin A Class II antiarrhythmic blocks ____________ channels. A) Potassium B) Beta C) Sodium D) Calcium A potential complication with the administration of a diuretic is ______________________. A) Hypothermia B) Hypernatremia C) Hypokalemia D) HypoglycemiaThe following items dose in micro-grama) Amlodipine b) Ceftrixone c) Ceftazidime d) Atropine
- Which of the following medications is a beta blocker? A) Hydrochlorothiazide B) Lasix C) Atenolol D) Simvastatin Which of the following is a contraindication to the antiarrhythmic Amiodarone? A) Tachycardia B) Allergy to Lidocaine C) Bradycardia D) Hypertension Which of the following is a common side effect of cholesterol medication? A) Muscle pain B) Diabetes C) Headache D) Decreased urination Which of the following most accurately describes the mechanism of action of a "statin"? A) Inhibits platelet aggregation B) Inhibits sodium excretion in the kidneys C) Inhibits cholesterol production in the liver D) Inhibits sodium reabsorption in the loop of Henle Which of the following is an indication to the antiarrhythmic Amiodarone? A) Bradycardia B) Hypercalcemia C) Hypertension D) Supraventricular Tachycardia (SVT)This drugs in the picture can treat: A) malaria B) cough C) pain D) arrhythmiaThe nurse caring for a patient who is receiving betal agonist drug therapy needs to be aware that these drugs cause which effect? a )Increased cardiac contractility b) Decreased heart rate c )Bronchoconstriction d)Increased Gl tract motility
- 12) A contraindication to ACE inhibitor administration is ____________________________. A) Respiratory Distress B) Chest Pain C) Allergy to Aspirin D) Hypotension13) Which of the following best describes the mechanism of an antiplatelet medication? A) Inhibition of platelet aggregation B) Blocking of sodium channels C) Inhibition of the inflammatory response D) Inhibition of factor X conversionHO Acetaminophen is prescribed more frequently in hospitals than aspirin is due to the fact that acetaminophen is NOT IZ CH3 A) An anticoagulant B) An antipyretic C) An anti-inflammatory D) Synthetic