1. Answer the following questions, based on this reaction: S+E ES EP= E+P A)What is the slow step of this reaction, and why is that step slow?

Biochemistry
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Chapter1: Biochemistry: An Evolving Science
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1. Answer the following questions, based on this reaction:

\[ S + E \rightleftharpoons ES \rightleftharpoons EP \rightleftharpoons E + P \]

A) What is the slow step of this reaction, and why is that step slow?

**Explanation:**

The diagram represents a sequence of reactions involving the formation and transformation of enzyme-substrate (ES) and enzyme-product (EP) complexes. Here’s a breakdown:

- **S** is the substrate.
- **E** is the enzyme.
- **ES** is the enzyme-substrate complex.
- **EP** is the enzyme-product complex.
- **P** is the product.

Each double arrow signifies that the reactions are reversible. The transition from **ES** to **EP** is often considered the rate-limiting step, meaning it is the slowest part of the sequence, typically due to factors like energy barriers or conformational changes in the enzyme.
Transcribed Image Text:1. Answer the following questions, based on this reaction: \[ S + E \rightleftharpoons ES \rightleftharpoons EP \rightleftharpoons E + P \] A) What is the slow step of this reaction, and why is that step slow? **Explanation:** The diagram represents a sequence of reactions involving the formation and transformation of enzyme-substrate (ES) and enzyme-product (EP) complexes. Here’s a breakdown: - **S** is the substrate. - **E** is the enzyme. - **ES** is the enzyme-substrate complex. - **EP** is the enzyme-product complex. - **P** is the product. Each double arrow signifies that the reactions are reversible. The transition from **ES** to **EP** is often considered the rate-limiting step, meaning it is the slowest part of the sequence, typically due to factors like energy barriers or conformational changes in the enzyme.
Expert Solution
Step 1 Introduction

In SN2 tpe of reaction, one bond is broken and one bond is formed synchronously, .

In one step. SN2 is a kind of nucleophilic substitution reaction mechanism.

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