1) Which of the following is not an important consideration for protecting groups? a. The protecting group must be able to be removed under mild conditions b. The protecting group must be unreactive under the conditions for another desired reaction c. The protecting group must be bulky to prevent access to nucleophilic sites d. The protecting group must be able to be added under conditions that will not cause other groups to react e. The protection and deprotection should consist of a single reaction each

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Chapter1: Chemical Foundations
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1) Which of the following is not an important consideration for protecting
groups?
a. The protecting group must be able to be removed under mild
conditions
b. The protecting group must be unreactive under the conditions for
another desired reaction
c. The protecting group must be bulky to prevent access to nucleophilic
sites
d. The protecting group must be able to be added under conditions that
will not cause other groups to react
e. The protection and deprotection should consist of a single reaction
each
Transcribed Image Text:1) Which of the following is not an important consideration for protecting groups? a. The protecting group must be able to be removed under mild conditions b. The protecting group must be unreactive under the conditions for another desired reaction c. The protecting group must be bulky to prevent access to nucleophilic sites d. The protecting group must be able to be added under conditions that will not cause other groups to react e. The protection and deprotection should consist of a single reaction each
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