. What can you infer about the inheritance of the FGFR alleles? A) The mutant FGFR3 allele is pleiotropic. B) Some achondroplastic dwarfs are heterozygous for the mutant allele and some are homozygous. C) The wild-type and mutant FGFR3 alleles are codominant. D) The mutant FGFR3 allele shows incomplete penetrance. 2. If two people with achondroplasia have a child together, what is the probability that their child will also have achondroplasia? A)0 B)1/2 C)2/3 D) 3/4 E)1
Achondroplasia is a form of dwarfism in humans. It is caused by a mutant allele of the fibroblast growth factor receptor 3 gene ( FGFR3) that produces an overactive protein. Having one copy of the mutant allele results in dwarfism. Two copies of the mutant allele results in death before birth. The mutant FGFR3 allele is completely penetrant.
1. What can you infer about the inheritance of the FGFR alleles?
A) The mutant FGFR3 allele is pleiotropic.
B) Some achondroplastic dwarfs are heterozygous for the mutant allele and some are homozygous.
C) The wild-type and mutant FGFR3 alleles are codominant.
D) The mutant FGFR3 allele shows incomplete penetrance.
2.
If two people with achondroplasia have a child together, what is the probability that their child will also have achondroplasia?
A)0
B)1/2
C)2/3
D) 3/4
E)1
a gene that, if homozygous, can block an organism's development or cause it to die.
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