1.2.3. Forensic Toxicology (1).pdf
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Georgetown University *
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Subject
Chemistry
Date
Jan 9, 2024
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Forensic
Toxicologist
What they
do
Summarize the next task we have
to
do
in
regards
to
Anna’s
autopsy.
Write 2-3 sentences in order to
relate each of these terms to one
another. Highlight each term. Use
your own words. Terms: Digestive
System, forensic toxicologist,
medical examiner, samples, toxin,
poison.
Why we need toxicology
tests
Could a chemical in the lab
where
she was found have caused
Anna’s death
? Is it possible that
she ingested something that
harmed her?
1.2.3. Forensic Toxicology
Looking for a Needle in a Haystack
Investigate what substances that could
have been in her system at the time of her
death. Potential harmful substances or
particularly toxins.
A
forensic
toxicologist
analyzes
the
contents in the
digestive system
. During an
autopsy, the
medical examiner
collects
samples
to check for
toxins
or
poison
.
To correctly determine the
substances within a body and the
effects they may have on humans
They look for poisons or
toxins in the body to study
and figure out how they
affect people
Physical vs. Chemical
Digestion:
Write 2-3 sentences in order to relate each of
these terms to one another. Highlight each
term. Use your own words. Terms: digestion,
nutrients, molecules, waste, chemical
reactions, energy.
Label each diagram as to whether it represents chemical or physical digestion.
Describe what each kind of digestion is and where it occurs.
Digesting the Digestive System
We eat and drink water and food substances for
energy, when we eat we digest the food to absorb
through chemical reactions, the molecules that give
us energy and power our body parts, the parts of
the food that are needed or leftover are excreeted
as waste.
Physical, the solid form and how we
perceive it, While there are many chemical
parts in it we perceive it as a different thing
such as a sandwich, this is also how the
digestion process begins
Chemical digestion: what the
substances are made of, the body cuts
out and used the parts that would
power and be useful to the body
Forensic
Chemist
What they test
Write a sentence to relate these terms. Use
your own words. Terms: metabolism,
metabolites, tissues, ingested chemicals.
In the boxes, list & describe each section of the
digestive system shown above in the order in which
materials pass through them.
The 2 kinds of tests they run
Inside Anna’s Stomach
Esophagus- muscular tube that
transports food from mouth
Stomach - contains acids and
enzymes
and contracts to break down food
Small intestine- break down food
molecules and absorbs digested
nutrients
Large intestine- reabsorbs water and
forms feces to be released from the
body
Metabolism
is the process of breaking down
substances and converting to new substances. The
small molecules produced are called
metabolites
.Toxicologists test samples of bodily
fluids and/or
tissues
for
ingested chemicals
in the
body.
Oral cavity - is the first part of the
digestive tract.
A forensic chemist is a professional chemist who
analyzes evidence that is brought in from crime scenes
and reaches a conclusion based on tests run on that
piece of evidence.
Presumptive tests and
confirmatory tests.
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Hypothesis
Independent Variable
Experimental Problem:
Known Substances
Dependent Variable
Things to Keep Constant: 1) 2) 3)
Ecstasy
(name & describe each, filling in what’s missing)
What is the pill that is in her stomach ?
Type of substance
Mixtures
Acetylsalicylic acid
Oxycodone
Acetaminophen
Common painkiller
Opiod painkiller; requires
prescription to obtain it but
is a commonly abused
prescription drug
Painkiller available over
the counter, very common
1) Amount
2) Powder
3) Same person
Illicit drug; commonly
found on college
campuses
I believe that the unknown chemical is acetaminophen.
As you complete the
lab,
record
what
happened in each well.
Use NR for no reaction.
Anna’s Toxicology Report
Substances Present in Anna’s
Blood
Levels of Each Substance & Meaning of Levels
Toxicology Analysis
Based on the results, what was the unknown chemical? Can we be CERTAIN that this is the actual identity of
the
Explain by discussing your data in detail.unknown substance? Explain, using the terms
presumptive, confirmatory & chromatography in your
answer.
Forensic Toxicology Lab
In each of the wells either there was a color change or texture
change.
color
bubbles
foam
odor
The unknown chemical was
oxycodone as evidenced by the
toxicology tests, It also fits in
with the investigation evidence
Caffine
Asprin
10 MGL
20 MGL
NR
NR
NR
gas
formation
NR
NR
NR
gas
formation
gas
formation
Yes we can be certain because
the unknown matched with
oxycodone on the PH and
multiple other categories.
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Fruity smell to it
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