Review for Molecules and Cells Exam #1 (1).docx

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1. If a base molecule (many copies of it) is added to a beaker of pure water, the pH will a. go up b. go down c. stay the same because water can donate protons 2. How does the relationship between water and hydrophobic molecules help to organize biological systems? a. Because water molecules preferentially associate with each other, they force hydrophobic molecules to associate with each other and not with water molecules b. Because cells are not pure water (they have many substances dissolved within them), the hydrophilic/hydrophobic effect has a limited role in biological organization c. The ionic bonds between water molecules cause hydrophobic molecules to associate with each other and not with water molecules. 3. The molecule to the right depicts a a. a carbohydrate b. a nucleotide c. a lipid d. an amino acid 4. Which make up an important part of a charged tRNA? a. nucleotide b. carbohydrate c. lipid d. amino acid e. a and b f. a and c e. a and d f. b and c g. b and d h. a, b, and d 5. Which is NOT true of double-stranded DNA structure? a. G-C basepairs share more electrons than do A-T base pairs d. a and b g. a, b, and c b. the two strands are identical when written 5’ to 3' e. b and c h. none (all are true) c. each strand of DNA must have a 5’ end and a 3’ end f. a and c 6. Genetic code charts list amino acids next to their a. codon b. anti-codon c. both d. neither 7. What is the name of the bond formed between two nucleotides in a nucleic acid? a. glycosidic bond c. phosphoanhydride bond e. peptide bond b. ester bond d. phosphodiester bond f. hydrogen bond 8. How many phosphates are required on an incoming nucleotide in order for it to be added to a growing nucleic acid chain? a. three b. zero c. two d. one e. four 9. Which is NOT normally found in RNAs? a. guanine b. nitrogen atoms c. thymine d. adenine e. ribose f. phosphate 10. Which is considered part of the backbone of DNA? a. nitrogenous bases b. deoxyribose c. phosphate d. amino groups d. a and b e. b and c f. c and d g. a and c h. b and c i. all of the above j. none of the above
11. Which would at least sometimes contain multiple Shine-Dalgarno sequences? a. eukaryotic genome b. eukaryotic mRNA c. eukaryotic proteins d. a & b e. a, b, c f. prokaryotic genome g. prokaryotic mRNA h. prokaryotic proteins i. f & g j. f, g, h 12. Where does mRNA “processing” (capping, splicing, polyadenylation) occur? a. prokaryotic cytoplasm b. eukaryotic cytoplasm c. in the ribosomal large subunit d. a and b e. none of the above 13. For a gene sequence that is found in double-stranded DNA and is “read” from right to left as shown, which correctly lists the order of sequences from left to right that would be found in and around this gene? a. promoter, start codon, terminator, stop codon b. stop codon, terminator, start codon, promoter g. start codon, stop codon, promoter, terminator c. stop codon, promoter, start codon, terminator h. stop codon, terminator, promoter, start codon d. terminator stop codon, promoter, start codon i. terminator, stop codon, start codon, promoter e. start codon, promoter, terminator, stop codon j. start codon, promoter, terminator, stop codon f. promoter, start codon, stop codon, terminator 14. During the translational elongation, a. an amino acid in the A site is transferred to a growing chain attached to the transfer RNA in the P site b. an amino acid in the E site is transferred to a growing chain attached to the transfer RNA in the P site c. an amino acid in the P site is transferred to a growing chain attached to the transfer RNA in the E site d. a growing chain attached to the transfer RNA in the P site is transferred to an amino acid in the A site e. a growing chain attached to the transfer RNA in the E site is transferred to an amino acid in the A site This image of double-stranded DNA refers to questions 15. 5’AAGTTAGTGTGATCGATCGATGGAAGCACTCTACTAGATTCTCAATAG 3’ 3’TTCAATCACACTAGCTAGCTACCTTCGTGAGATGATCTAAGAGTTATC 5’ 15. Which of the following mRNAs could hypothetically be transcribed from this sequence? (Assume for this hypothetical situation that no special start and stop sequences are needed.)
a. 5’ UUCAAT 3’ b. 3’ UUCAAU 5’ c. 3’ AAGUUA 5’ d. 5’ AAGUUA 3’ e. none of the above 16. Which of the following peptides could hypothetically translated based on this sequence? a. Lys-Leu-Val c. Tyr-Leu-Arg-Glu-Met-Ile e. Met-Ile g. more than one of the above b. Phe-Asn-His-Thr-Ser d. Met-Glu-Ala-Leu-Tyr f. Asp-Asn-Ser h. none of above 17. Which would be a product of this mRNA? a. Met-Tyr c. Pro-His b. Gly-Val (more a.a.) d. Met-Pro-His e. none of the above 18. What is the anticodon for methionine (Met)? a. 5’ TAC 3’ b. 5’ CAT 3’ c. 3’ GUA 5’ d. 5’ AUG 3’ e. none of the above 19. Is this molecule amphipathic? Is it saturated or unsaturated? 20. Which amino acid is the special one that has no R group? (Check all that apply) a. Cysteine b. Methionine c. Glycine d. Proline 21. Which component of a phospholipid is found in the interior of a lipid bilayer? a. Glycerol b. Fatty acids c. phosphate group d. Protein 22. Which one of the following is considered an integral membrane protein? a. A protein with its N-terminus in the cytoplasm and its C-terminus in the extracellular space a. A protein attached to a transmembrane protein via hydrogen bonding b. A protein attached to a phospholipid via iconic bonding with the head group of the lipid molecule c. A protein capable of diffusing throughout the cytoplasm of a cell 23. How many different types of amino-acyl tRNA synthases are there in a cell? a. 1 a. 3
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b. 4 c. 20 d. 26 24. Where is tRNA synthesized in a eukaryotic cell? a. Nucleus a. Cytoplasm b. ER c. Ribosome 25. Which nucleotide base pairing has the highest amount of hydrogen bonds? a. G to C a. A to T b. A to U c. T to G d. All are equal 26. Which strand in a DNA double helix acts as the template for mRNA? a. 5’ to 3’ b. 3’ to 5’ 27. How many outer shell valence electrons does a Carbon atom have? a. 1 a. 2 b. 4 c. 6 d. 20 28. What is attached to the 5’ Carbon in a DNA molecule? a. Phosphate group b. Hydroxyl group c. nitrogenous base d. tRNA 29. What is attached to the 5’ Carbon in an RNA molecule? a. Phosphate group b. Hydroxyl group c. nitrogenous base d. tRNA 30. Which carbon in an RNA nucleotide can attach to uracil? a. 1’ b. 2’ c. 3’ d. 4’ e. 5’ 31. Which can normally be found in the cytoplasm of eukaryotic cells? (select all that apply) a. Ribosomal subunits b. Intron sequence c. DNA d. Exon sequences e. none of the above 32. Which of the following is NOT part of a prokaryotic cell? a. DNA b. Plasma membrane c. integral membrane proteins d. Ribosomes 33. How many membranes does a chloroplast have? a. 0 b. 1 c. 2 d. 3 e. 4
34. Where is tRNA synthesized in a prokaryotic cell? a. Nucleus b. Cytoplasm c. ER d. Ribosome 35. Which part of a DNA nucleotide holds the genetic information? a. Sugar phosphate backbone a. 2’ carbon b. Ribose c. nitrogenous base 36. If an amino acid is encoded by the codon GAA, which of the following is the anticodon on the tRNA? a. 5’UUC3’ a. 5’CUU3’ b. 5’AAG3’ c. 5’GAA3’ 37. What is the function of endocytosis? a. To export things out of the cell a. To import things into the cell b. To absorb heat c. To release heat 38. What force is exerted on the cell wall? a. Friction force b. Turgor pressure c. osmotic pressure d. Partial pressure 39. Which of the following is NOT true about ATP synthase? a. It is a membrane-spanning protein complex a. Is utilizes ADP as a substrate b. It binds and releases hydrogen ions to complete its tasks c. It is an antiporter d. None of the above 40. What enzymes are in peroxisomes? a. Reductive enzymes b. Catalase c. peroxidase d. Kinase 41. What does ATP synthase directly use to make ATP? a. Light b. More ATP c. Proton gradient d. Glucose 42. If a solution is hypertonic to a cell, the solution has ______ solute than the cell and the cell will ______.
a. More; lyse a. More; shrink b. Less; lyse c. Less; shrink 43. Which of these statements regarding mRNA is false: a. A shine-dalgarno sequence tells a prokaryotic ribosome where to bind a. A TATA box signals the beginning of transcription for both eukaryotes and prokaryotes b. A prokaryote can make polycistronic mRNA a eukaryote cannot c. Prokaryotic mRNA does not include uracil d. A eukaryote makes its mRNA in the nucleus, a prokaryote does not 44. How many membranes does a mitochondria have? a. 0 b. 1 c. 2 d. 3 e. 4 45. What type of bond holds a string of nucleotides together in a chain of a single stranded DNA? a. Peptide bond b. Phosphodiester bond c. nucleotide bond d. Ionic bond 46. What term is used to describe the type of mRNA that encodes multiple proteins? a. Polyaminocyl b. Polycistronic C. polypeptidic d. Polyribosomal 47. What maintains the lysosomal pH at 5? a. Aciditase b. Basitase c. Proton pump d. Hydroxyl pump 48. If the pH of a solution changes from 2.3 to 5.3, the [H+] changed by ___ ions: a. 100 b. 1000 c. 2 d. 2000 49. Which are unique to (only present in) eukaryotic transcription? (select all that apply) a. Enhancers b. Sigma c. mediator complex d. Promoter 50. What is the sequence of initiation in translation? a. Large subunit small subunit tRNA a. Small subunit large subunit tRNA b. tRNA small subunit large subunit c. Small subunit tRNA large subunit 51. Select the following that use energy: a. Facilitated a. Primary b. Simple c. Secondary
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