case study wk 5

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Cedar Crest College *

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255

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Biology

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Apr 3, 2024

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docx

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4

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2 Question 1 The human immune system protects the body against pathogens, but sometimes it overreacts, resulting in detrimental consequences. Hypersensitivity reactions are inapt or exaggerated immune retorts against allergens or antigens ( Saladin, 2019) . The clinical symptoms of hypersensitive reactions include sneezing, rashes, and shortness of breath, among others. Question 2 Hypersensitive reactions into four distinct types. Type 1 hypersensitivity, commonly referred to as an anaphylactic response, occurs when IgE antibodies respond to environmental allergens like pollens or dust mites (Vaillant et al., 2022). Anaphylaxis or Type II hypersensitivity is also mediated by IgE antibodies, where mast cells produce hefty histamine and leukotrienes. Type III hypersensitivity is mediated by immune complexes and involves three essential antibodies, IgM, IgG, and IgA. Lastly, Type IV is a delayed hypersensitive reaction mediated by T-cells activation caused by cytokine release ( Saladin, 2019) . Question 3 Manuel is experiencing Type II hypersensitivity reaction or Anaphylaxis. According to Saladin (2019), clinical symptoms of Anaphylaxis include respiratory failure and skin reactions such as hives and itching. Manuel experiences shortness of breath and has generalized hives on his face and upper body, indicating Anaphylaxi (Saladin, 2019). Question 4 Anaphylaxis is an antibody-mediated response. This hypersensitive reaction involves Immunoglobulin E (IgE) antibodies (Vaillant et al., 2022). IgE antibodies are generated in response to insect venoms, medications, or foods. Question 5
3 Epinephrine was administered to reduce swelling in the airways and increase blood flow in the veins since Manuel was experiencing breathing difficulties. As Sicherer et al. (2017) assert, epinephrine subsides or prevents constriction of upper airway muscles. As such, a dose of epinephrine, in this case, will signal Manuel's veins to dilate, pump more blood and relax his muscles, ultimately returning his blood flow and breathing to normal.
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4 References Saladin, K. S. (2019). Anatomy and Physiology: The Unity of Form and Function, 4th, 2004. 443-558. Sicherer, S. H., Simons, F., Mahr, T. A., Abramson, S. L., Dinakar, C., Fleisher, T. A.,Irani, A.,Kim, J.S., & Matsui, E. C. (2017). Epinephrine for first-aid management of anaphylaxis. Pediatrics, 139 (3), 2. https://doi.org/10.1542/peds.2016-4006. Vaillant, A. A. J., Vashisht, R., & Zito, P. M. (2022). Immediate hypersensitivity reactions. In   StatPearls [Internet] . StatPearls Publishing. https://www.ncbi.nlm.nih.gov/books/NBK513315/.