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Q3.1 14) The cells that express the growth hormone (GH) gene are this component of the homeostatic system. 0.5 Points Stimulus None of the choices Response Effector Sensor Q3.2 Explain your reasoning for selecting the answer you chose above for Q3.1 0.5 Points You are not obligated to agree with your teammates on any answer.

Be mindful not to plagiarize. Use your own words or reference your sources. In this case, the hypothalamus is the sensor, the level of ghrelin is the stimulus, the liver is the effector, and the response would be the increased fat synthesis and appetite. The anterior pituitary would appear to be just an intermediate in this homeostatic system, so none of the above. Q3.3 17) The hypothalamus releasing GHRH to stimulate GH release from the anterior pituitary is an example of _______ feedback. 0.5 Points positive positive and negative neither positive nor negative negative Q3.4 Explain your reasoning for selecting the answer you chose above for Q3.3 0.5 Points You are not obligated to agree with your teammates on any answer. Be mindful not to plagiarize. Use your own words or reference your sources. Release of GH is neither negative nor positive since it doesn’t lead to further hormone release and it also doesn’t inhibit the release of GH or GHRH in an immediate cycle.

Q4 1 Point [Question 22-26] Glucocorticoids (GCs) are signals that increase in response to stress. Corticosteroid-binding globulin is synthesized by the liver and secreted into the bloodstream where it binds to GCs for transport. GCs are secreted by the adrenal gland in response to adrenocorticotrophic hormone (ACTH). ACTH is produced by the anterior pituitary when signal peptide corticotropinreleasing hormone (CRH) is released by the hypothalamus in times of stress. Glucocorticoids have a wide range of physiological effects regulating metabolism, immune function, behavior and cognitive functions, as well as reproduction. GCs also regulate their own secretion by a negative feedback mechanism. GCs can inhibit release of GnRH from the hypothalamus, inhibiting testosterone synthesis while also influencing gametogenesis. Use this information and the illustration below to answer the following questions.

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Q4.1 24) Cells that express the ACTH receptor gene are this component of a homeostatic feedback loop.

0.5 Points Stimulus Response None of the choices Sensor Effector

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