Microbiology Fundamentals: A Clinical Approach
3rd Edition
ISBN: 9781259709227
Author: Marjorie Kelly Cowan Professor, Heidi Smith
Publisher: McGraw-Hill Education
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Chapter 9.2, Problem 5AYP
Summary Introduction
To name:
The six methods of physical control of microorganisms.
Concept introduction:
The term microbial control refers to killing or inhibiting the growth of the microorganisms such as viruses, bacteria, and
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19. On the diagram below
a. Label the three pictures as: DNA; polypeptide; or RNA.
b. Label the arrows as: translation or transcription/RNA processing.
c. Add the following details to the diagram.
Promoter region
TATA box
Transcription start site
Transcription terminator
Intron (A,B,C,D)
Exons (1,2,3,4,5)
Splice sites
5' cap
5' UTR (untranslated region)
3' poly A tail
3' UTR (untranslated region)
Translational start (AUG)
Translational stop (UGA, UAG, or UAA)
N and C ends of polypeptide
0000
Match the letter labels in the figure below to the terms. Some letter
labels are not used.
MNNNNNNIN
M
C
B
A
M
D
F
E
H
K
G
8
The diagram below illustrates a quorum sensing pathway from Staphylococcus aureus. Please answer the following questions.
1. Autoinduction is part of the quorum sensing system. Which promoter (P2 or P3) is critical for autoinduction?
2)This staphylococcus aureus grows on human wounds, causing severe infections. You would like to start a clinical trial to treat these wound infections. Please describe:
a) What molecule do you recommend for the trial. Why?
b) Your trial requires that Staphylococcus aureus be isolated from the wound and submitted to genome sequencing before admittance. Why? What are you testing for?
3) If a mutation arises where the Promoter P3 is constitutively active, how would that influence sensitivity to AIP? Please explain your rationale.
4) This pathway is sensitive to bacterial cell density. Describe two separate mutation that would render the pathway active independent of cell density. Briefly explain your rationale.
Mutation 1
Mutation 2
Chapter 9 Solutions
Microbiology Fundamentals: A Clinical Approach
Ch. 9.1 - Clearly define the terms sterilization,...Ch. 9.1 - Prob. 2AYPCh. 9.1 - Compare the action of microbicidal and...Ch. 9.1 - Name four categories of cellular targets for...Ch. 9.2 - Prob. 5AYPCh. 9.2 - Prob. 6AYPCh. 9.2 - Prob. 7AYPCh. 9.2 - Prob. 8AYPCh. 9.2 - Prob. 9AYPCh. 9.2 - Prob. 10AYP
Ch. 9.2 - Differentiate between the two types of radiation...Ch. 9.2 - Prob. 12AYPCh. 9.3 - Name the desirable characteristics of chemical...Ch. 9.3 - Prob. 14AYPCh. 9.3 - List advantages and disadvantages to phenolic...Ch. 9.3 - Prob. 16AYPCh. 9.3 - Prob. 17AYPCh. 9.3 - Identify some heavy metal control agents.Ch. 9.3 - Prob. 19AYPCh. 9.3 - Identify applications for ethylene oxide...Ch. 9.3 - Prob. 1MMCh. 9.3 - Prob. 2NPCh. 9.3 - Q. What is the mode of action of chlorhexidine?Ch. 9.3 - In the health care environment, use of...Ch. 9 - Prob. 1NPCh. 9 - Prob. 1QCh. 9 - Prob. 2QCh. 9 - Triclosan and other antimicrobial compounds have...Ch. 9 - Microbial control methods that kill _____ are able...Ch. 9 - Prob. 5QCh. 9 - Prob. 6QCh. 9 - Prob. 7QCh. 9 - Prob. 8QCh. 9 - Prob. 9QCh. 9 - Prob. 10QCh. 9 - Do you think UV radiation is a good way to...Ch. 9 - Suggest a possible mechanism for how a microbe...Ch. 9 - Prob. 13QCh. 9 - Prob. 14QCh. 9 - What additional considerations would you have to...Ch. 9 - Sanitization is a process by which a. the...Ch. 9 - Prob. 17QCh. 9 - Defend this statement: It is possible to make our...Ch. 9 - The most versatile method for sterilizing...Ch. 9 - Precisely what is microbial death?Ch. 9 - Prob. 21QCh. 9 - From chapter 3, figure 3.15. Study this...
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