Chapter 9.11, Problem 9.8CIAP

Interpretation Introduction

Interpretation:

Reason for using hygroscopic material in the transdermal patches has to be identified.

Concept introduction:

• Many medications are more effective if coated or protected with a substance that reacts slowly in the body during digestion, releasing the medication in the appropriate tissue.
• Some early timed-release medications were encased in a polymer coating that dissolved slowly.
• Enteric coatings dissolve in base, so release the medication only after arriving in the intestine.
• Osmotic pumps release medication from a compartment slowly as a second compartment absorbs moisture from air or body fluids.
• Transdermal patches allow a noninvasive method of delivering medications over time.