ELEMENTS OF CHEM. REACTION ENGR
5th Edition
ISBN: 9780135486498
Author: Fogler
Publisher: INTER PEAR
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Textbook Question
Chapter 9, Problem 9.10P
It has been observed that substrate inhibition occurs in the following enzymatic reaction:
E + S → P + E
- (a) Show that the rate law for substrate inhibition is consistent with the plot in Figure P9-10B of −rs (mmol/L · min) versus the substrate concentration S (mmol/L).
- (b) If this reaction is carried out in a CSTR that has a volume of 1000 dm3, to which the volumetric flow rate is 3.2 dm3/min, determine the three possible steady states, noting, if possible, which are stable. The entrance concentration of the substrate is 50 mmol/dm3. What is the highest conversion?
- (c) What would be the effluent substrate concentration if the total enzyme concentration is reduced by 33%?
- (d) List ways you can work this problem incorrectly.
- (e) How could you make this problem more difficult?
Figure P9-10B Michaelis–Menten plot for substrate inhibition.
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Chapter 9 Solutions
ELEMENTS OF CHEM. REACTION ENGR
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