BIOLOGY 2E
2nd Edition
ISBN: 9781506699851
Author: OpenStax
Publisher: XANEDU PUBLISHING
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Chapter 9, Problem 5RQ
What property prevents the ligands of cell-surface receptors from entering the cell?
- The molecules bind to the extracellular domain.
- The molecules are hydrophilic and cannot penetrate the hydrophobic inferior of the plasma membrane.
- The molecules are attached to transport proteins that deliver them through the bloodstream to target cells.
- The ligands are able to penetrate the membrane and directly influence gene expression upon receptor binding.
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3) The “Met" receptor is a membrane receptor protein responsible for initiating signal
transduction pathways that cause cells to divide, among other things.
After the Met receptor has been stimulated by its specific growth factor, another protein called c-
Cbl will bind to the Met receptor. C-Cbl will then attach a chain of small proteins called ubiquitin
to the Met receptor. These chains of ubiquitin help the cell recognize that the Met receptor should
undergo receptor-mediated endocytosis, which eventually leads to the destruction of the Met
receptor.
Circle any answer or answers that include mutations that could cause the cell to potentially
become a cancer cell.
A) a mutation causing there to be too much ubiquitin protein produced.
B) a mutation causing c-Cbl to be inactivated.
C) a mutation causing ubiquitin to be inactivated.
D) a mutation causing there to be too few Met receptors produced.
E) a mutation causing the Met receptor to no longer be able to bind to its growth factor.…
The G protein coupled receptor (GPCR) pathway elicits diverse intracellular responses in different cells. The basic steps of GPCR signaling are outlined in this diagram.
Which of the following statements correctly describes the process of GPCR signaling?
The GPCR activation is reversible after the signal of the ligand diminishes.
The membrane-embedded enzyme uses GTP as a secondary messenger to initiate gene expression.
The ligand attaches to both the GPCR and the membrane-embedded enzyme to activate the GPCR pathway.
The ligand-bound GPCR sends a GTP molecule to an enzyme in the membrane and switches it into an active state.
Which of the following is a type of signal transduction pathway controlling gene expression?
All of these
Protein subunit dissociation pathway
Receptor-associated kinase pathway
None of these
Cytosolic kinase pathway
Chapter 9 Solutions
BIOLOGY 2E
Ch. 9 - Figure 9.8 HER2 is a receptor tyrosine kinase. In...Ch. 9 - Figure 9.10 In certain cancers, the GTPase...Ch. 9 - Figure 9.17 Which of the following statements...Ch. 9 - Figure 9.18 What advantage might biofilm...Ch. 9 - What property prevents the ligands of cell-surface...Ch. 9 - The secretion of hormones by the pituitary gland...Ch. 9 - Why are ion channels necessary to transport ions...Ch. 9 - Endocrine signals are transmitted more slowly than...Ch. 9 - A scientist notices that when she adds a small,...Ch. 9 - Where do DAG and IP3 originate? They are formed by...
Ch. 9 - What property enables the residues of the amino...Ch. 9 - Histamine binds to the H1 G-protein-linked...Ch. 9 - A scientist observes a mutation in the...Ch. 9 - What is the function of a phosphatase? A...Ch. 9 - How does NF-kB induce gene expression? A small,...Ch. 9 - Apoptosis can occur in a cell when the cell is...Ch. 9 - What is the effect of an inhibitor binding an...Ch. 9 - How does PKC’s signaling role change in response...Ch. 9 - A scientist notices that a cancer cell line fails...Ch. 9 - Which type of molecule acts as a signaling...Ch. 9 - Quorum sensing is triggered to begin when...Ch. 9 - A doctor is researching new ways to treat biofilms...Ch. 9 - What is the difference between intracellular...Ch. 9 - How are the effects of paracrine signaling limited...Ch. 9 - What are the differences between internal...Ch. 9 - Cells grown in the laboratory are mixed with a dye...Ch. 9 - Insulin is a hormone that regulates blood sugar by...Ch. 9 - The same second messengers are used in many...Ch. 9 - What would happen if the intracellular domain of a...Ch. 9 - If a cell developed a mutation in its MAP2K1 gene...Ch. 9 - What is a possible result of a mutation in a...Ch. 9 - How does the extracellular matrix control the...Ch. 9 - A scientist notices that a cancer cell line shows...Ch. 9 - What characteristics make yeasts a good model for...Ch. 9 - Why is signaling in multicellular organisms more...Ch. 9 - Pseudomonas infections are very common in hospital...
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