Essentials of Biology (5th International Edition)
5th Edition
ISBN: 9781259660269
Author: Sylvia S. Mader, Dr., Michael Windelspecht
Publisher: Mcgraw-Hill
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Chapter 9, Problem 1TC
Although most men with Klinefelter syndrome are infertile, some are able to father children. It was found that most fertile individuals with Klinefelter syndrome exhibit mosaicism, in which some cells are normal (46, XY) but others contain the extra chromosome (47, XXY). How might mosaicism come about? What effects might result?
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I am a little confused on this question.
In com, male sterility is controlled by maternal cytoplasmic elements. However, the presence of a nuclear fertility restorer gene (F_) restores fertility to male sterile lines.
a. What are the crosses male sterile female x FF male? Give the genotypes and phenotypes of the offspring in each cross. Explain.
How many Barr bodies are present in the interphase cells of the ff. individuals? A) Klinefelters where
2n = 48 (assume no autosomal aneuploidy in this individual) (b) metafemales with chromosome
number of 48 (no autosomal aneuploidy in this individual). Show solutions.
Chapter 9 Solutions
Essentials of Biology (5th International Edition)
Ch. 9.1 - Explain the purpose of meiosisCh. 9.1 - Prob. 2LOCh. 9.1 - Prob. 3LOCh. 9.1 - Prob. 4LOCh. 9.1 - Prob. 1CYPCh. 9.1 - Prob. 2CYPCh. 9.1 - Prob. 3CYPCh. 9.1 - Prob. 4CYPCh. 9.1 - Prob. 1ACh. 9.1 - Prob. 2A
Ch. 9.2 - List the phases of meiosis, and briefly describe...Ch. 9.2 - Prob. 2LOCh. 9.2 - Prob. 1CYPCh. 9.2 - Prob. 2CYPCh. 9.2 - Prob. 3CYPCh. 9.2 - Prob. 3ACh. 9.2 - Prob. 4ACh. 9.2 - Prob. 5ACh. 9.2 - Prob. 6ACh. 9.2 - Prob. 7ACh. 9.2 - Prob. 8ACh. 9.2 - Prob. 9ACh. 9.2 - Prob. 10ACh. 9.2 - Prob. 11ACh. 9.3 - Contrast the events of meiosis I and meiosis II...Ch. 9.3 - Prob. 2LOCh. 9.3 - Prob. 1CYPCh. 9.3 - Prob. 2CYPCh. 9.3 - Summarize the major differences among the stages...Ch. 9.3 - Prob. 12ACh. 9.3 - Prob. 13ACh. 9.3 - Prob. 14ACh. 9.4 - Prob. 1LOCh. 9.4 - Prob. 2LOCh. 9.4 - Prob. 3LOCh. 9.4 - Describe how a zygote can receive an abnormal...Ch. 9.4 - Contrast monosomy with trisomy.Ch. 9.4 - Prob. 3CYPCh. 9.4 - Prob. 15ACh. 9.4 - Prob. 16ACh. 9 - Prob. 1BYBCh. 9 - Prob. 2BYBCh. 9 - Prob. 3BYBCh. 9 - Prob. S4.4BYBCh. 9 - Section 8.2 What events occur during prophase,...Ch. 9 - Prob. S8.2BYBCh. 9 - Although most men with Klinefelter syndrome are...Ch. 9 - Prob. 2TCCh. 9 - Prob. 3TC
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- An individual is heterozygous for a reciprocal translocation, with the following chromosomes: A • B C D E F A • B C V W X R ST • U D E F R ST • U V W X Q. Explain why the fertility of this individual is likely to be less than the fertility of an individual without a translocation.arrow_forwardLet’s say there is an organism with two pairs of alleles, W/w and Z/z, each pair is located on a different pair of chromosomes in the organism’s somatic cells. During Metaphase, what will you observe in the somatic cells?arrow_forwardPlease answer question (a) (b) and (e)arrow_forward
- A human female with Turner syndrome (45,X) alsoexpresses the X-linked trait hemophilia, as did her father.Which of her parents underwent nondisjunction during meiosis,giving rise to the gamete responsible for the syndrome?arrow_forwardWhy does a single X chromosome cause infertility and other abnormalities in Turner Syndrome subjects?arrow_forwardRetinoblastoma can be seen as a familial cancer, inherited in an autosomal recessive manner (RB-/RB-), individuals heterozygous for the RB+ and RB- alleles can develop tumor as a result of… A mitotic crossover that leads to homozygosity for RB+ in some cells and RB- in other cells A meiotic mutation in the RB+ allele that leads to homozygosity for RB+ A somatic mutation in the RB- allele that leads to homozygosity for RB+ The fact that RB- is dominant to RB+arrow_forward
- A woman with no phenotype is known to have a 14:21 translocation. Please answer questions 1 and 2. 1. With respect to only chromosomes 14 and 21, how many distinct chromosome combinations will happen in her eggs? What portion will be viable? 2. If she has children with a normal man (no translocations), what is the probability that they have a daughter with Down Syndrome or a son with no phenotype?arrow_forwardLet’s say there is an organism with two pairs of alleles, W/w and Z/z, each pair is located on a different pair of chromosomes in the organism’s somatic cells. During Prophase, what will you observe in the somatic cells?arrow_forwardA woman with a balanced reciprocal translocation of Chromosomes 4 and 20 (karyotype, right panel below) is trying to reproduce with a man of normal karyotype (left panel below). Please answer: 1) What are the karyotypes of their respective gametes ()? 2) What are the karyotypes of their potential offspring ()? 3) What are the percentages of each karyotype (gametes and offspring) ()? 4) Indicate which karyotype (of the offspring) will be lethal, carrier or normal (). 5) Do she have reduced fertility and why?arrow_forward
- An individual heterozygous for a reciprocal translocation possesses the following chromosomes: A B ● C D E F G, A B • C D V W X, R S •T U E F G, R S•T U V W Xa. Draw the pairing arrangement of these chromosomes in prophase 1 of meiosis. Mention their gametic composition. b. Draw the alternate, adjacent I, and adjacent II segregation patterns in anaphase I of meiosis. Mention their gametic composition.arrow_forwardn corn, male sterility is controlled by maternal cytoplasmic elements. This phenotype renders the male part of the corn plants (i.e the tassel) unable to produce fertile pollen; the female parts, however, remain receptive to pollination by pollen from male fertile corn plants. However, the presence of a nuclear fertility restorer gene F restores fertility to male sterile lines sing the cardboard chips, simulate the crosses indicated below. Give the genotypes and phenotypes of the offsprings in each cross, and properly label the nucleus and the cytoplasm of each individual in the cross Legend male sterile cytoplasm Male fertile cytoplasm FF nucleus Ff nucleus ff nucleus A. Male sterile female x FF male Explain the phenotype of the offspring B. Male sterile female x Ff male Explain the phenotype of the offspringarrow_forwardA young couple is planning to have children. Knowing that there have been a substantial number of stillbirths, miscarriages, and fertility problems on the husband’s side of the family, they see a genetic counselor. A chromosome analysis reveals that, whereas the woman has a normal karyotype, the man possesses only 45 chromosomes and is a carrier of a Robertsonian translocation between chromosomes 22 and 13. a. List all the different types of gametes that might be produced by the man. b. What types of zygotes will develop when each of gametes produced by the man fuses with a normal gamete produced by the woman? c. If trisomies and monosomies entailing chromosomes 13 and 22 are lethal, approximately what proportion of the surviving offspring are expected to be carriers of the translocation?arrow_forward
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