Essential Cell Biology (fifth Edition)
5th Edition
ISBN: 9780393680362
Author: ALBERTS, Bruce, Hopkin, Karen, Johnson -
Publisher: W. W. Norton & Company
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Chapter 9, Problem 19Q
Summary Introduction
To explain: Consequences of the fact that reverse transcriptase does not proofread while synthesizing DNA from an RNA template for the treatment of AIDS.
Concept introduction:
Reverse transcriptase is an enzyme used to generate complementary DNA from a template RNA strand. The process is called reverse transcription and is commonly seen in retroviruses. One of the major problems associated with the enzyme is its non-proof reading nature by which it is not able to correct any error produced in the respective coding stand. This feature is very much exploited by HIV viruses in replicating their genome.
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